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Prevalence of atrial septal defects and patent foramen ovale in a cohort of sudden cardiac death patients undergoing autopsy
CONCLUSIONS: The combined rate of PFO and ASD in a cohort of 517 patients undergoing autopsy was 7.9 %. None of these patients had experienced a cerebrovascular accident. This rate of PFOs appears lower than earlier reports and raises the possibility that the relative risk of an associated stroke could be higher than previously estimated.PMID:37734655 | DOI:10.1016/j.jjcc.2023.09.006
Source: Journal of Cardiology - September 21, 2023 Category: Cardiology Authors: Louise Fahy Stephanie Rowe Ziad Nehme Dion Stub Dominica Zentner Paul James Andreas Pflaumer Vanessa Connell Christopher Semsarian Jodie Ingles Andre La Gerche Elizabeth D Paratz Source Type: research

Persistent pathology of the patent foramen ovale: a review of the literature
Med J Aust. 2021 Jul 4. doi: 10.5694/mja2.51141. Online ahead of print.ABSTRACTA patent foramen ovale (PFO) is an interatrial shunt, with a prevalence of 20-34% in the general population. While most people do not have secondary manifestations of a PFO, some reported sequelae include ischaemic stroke, migraine, platypnoea-orthodeoxia syndrome and decompression illness. Furthermore, in some cases, PFO closure should be considered for patients before neurosurgery and for patients with concomitant carcinoid syndrome. Recent trials support PFO closure for ischaemic stroke patients with high risk PFOs and absence of other identi...
Source: Medical Journal of Australia - July 4, 2021 Category: General Medicine Authors: Kenneth K Cho Shaun Khanna Phillip Lo Daniel Cheng David Roy Source Type: research

Device closure for patent foramen ovale in patients with cryptogenic stroke: a paradigm in evidence.
Authors: Ha FJ, Adams H, Palmer S PMID: 31523821 [PubMed - as supplied by publisher]
Source: Medical Journal of Australia - September 17, 2019 Category: General Medicine Tags: Med J Aust Source Type: research

Advances in stroke medicine.
Authors: Campbell BC Abstract In recent years, reperfusion therapies such as intravenous thrombolysis and endovascular thrombectomy for ischaemic stroke have dramatically reduced disability and revolutionised stroke management. Thrombolysis with alteplase is effective when administered to patients with potentially disabling stroke, who are not at high risk of bleeding, within 4.5 hours of the time the patient was last known to be well. Emerging evidence suggests that other thrombolytics such as tenecteplase may be even more effective. Treatment may be possible beyond 4.5 hours in patients selected using brain imagi...
Source: Medical Journal of Australia - May 6, 2019 Category: General Medicine Tags: Med J Aust Source Type: research