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Novel Drug Delivery System for Curcumin: Implementation to Improve Therapeutic Efficacy against Neurological Disorders
Conclusion: The review also summarises the numerous toxicological studies and the role of curcumin in CNS disorders.PMID:34225614 | DOI:10.2174/1386207324666210705114058
Source: Combinatorial Chemistry and High Throughput Screening - July 6, 2021 Category: Chemistry Authors: Roohi Mohi-Ud-Din Reyaz Hassan Mir Taha Umair Wani Abdul Jalil Shah Ishtiyaq Mohi-Ud-Din Mudasir Ahmad Dar Faheem Hyder Pottoo Source Type: research

Effects of curcumin on neurological diseases: focus on astrocytes.
Abstract Astrocytes are the most abundant glial cells in the central nervous system, and are important players in both brain injury and neurodegenerative disease. Curcumin (1,7-bis[4-hydroxy-3-methoxyphenyl]-1,6-heptadiene-3,5-dione), the major active component of turmeric, belongs to the curcuminoid family that was originally isolated from the plant Curcuma longa. Several studies suggest that curcumin may have a beneficial impact on the brain pathology and aging. These effects are due to curcumin's antioxidant, free-radical scavenging, and anti-inflammatory activity. In light of this, our current review aims to d...
Source: Pharmacological Reports - May 26, 2020 Category: Drugs & Pharmacology Authors: Eghbaliferiz S, Farhadi F, Barreto GE, Majeed M, Sahebkar A Tags: Pharmacol Rep Source Type: research

Benefits of curcumin in brain disorders
AbstractCurcumin is widely consumed in Asia either as turmeric directly or as one of the culinary ingredients in food recipes. The benefits of curcumin in different organ systems have been reported extensively in several neurological diseases and cancer. Curcumin has got its global recognition because of its strong antioxidant, anti ‐inflammatory, anti‐cancer, and antimicrobial activities. Additionally, it is used in diabetes and arthritis as well as in hepatic, renal, and cardiovascular diseases. Recently, there is growing attention on usage of curcumin to prevent or delay the onset of neurodegenerative diseases. This...
Source: BioFactors - June 10, 2019 Category: Biochemistry Authors: Abid Bhat, Arehally M. Mahalakshmi, Bipul Ray, Sunanda Tuladhar, Tousif A. Hediyal, Esther Manthiannem, Jagadeeswari Padamati, Ramesh Chandra, Saravana B. Chidambaram, Meena K. Sakharkar Tags: REVIEW ARTICLE Source Type: research