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Effects of sotatercept on haemodynamics and right heart function: analysis of the STELLAR trial
Conclusion In pre-treated patients with PAH, sotatercept demonstrated substantial improvements in PA pressures, PA compliance, PA–RV coupling and right heart function.
Source: European Respiratory Journal - September 21, 2023 Category: Respiratory Medicine Authors: Souza, R., Badesch, D. B., Ghofrani, H. A., Gibbs, J. S. R., Gomberg-Maitland, M., McLaughlin, V. V., Preston, I. R., Waxman, A. B., Grünig, E., Kopec, G., Meyer, G., Olsson, K. M., Rosenkranz, S., Lin, J., Johnson-Levonas, A. O., de Oliveira Pena Tags: Original Articles: Pulmonary vascular disease Source Type: research

Effects of sotatercept on haemodynamics and right heart function: analysis of STELLAR trial
CONCLUSION: In pre-treated patients with PAH, sotatercept demonstrated substantial improvements in PA pressures, PA compliance, PA-RV coupling and right heart function.PMID:37696565 | DOI:10.1183/13993003.01107-2023
Source: Respiratory Care - September 11, 2023 Category: Respiratory Medicine Authors: Rogerio Souza David B Badesch H Ardeschir Ghofrani J Simon R Gibbs Mardi Gomberg-Maitland Vallerie V McLaughlin Ioana R Preston Aaron B Waxman Ekkehard Gr ünig Grzegorz Kope ć Gisela Meyer Karen M Olsson Stephan Rosenkranz Jianxin Lin Amy O Johnson-Levo Source Type: research

Chronic comorbid conditions and asthma exacerbation occurrence in a general population sample
In conclusion, several chronic comorbid conditions were associated with asthma exacerbation occurrence, which confirms but also complements previous studies. Our observations contribute to understanding exacerbation risk estimation and, ultimately, personalized asthma management.PMID:37567896 | DOI:10.1038/s41533-023-00350-x
Source: Respiratory Care - August 11, 2023 Category: Respiratory Medicine Authors: Emma Baljet Hilde Luijks Lisette van den Bemt Tjard R Schermer Source Type: research

Analysis of the clinical features and risk factors of kidney injury in patients with chronic heart failure-a retrospective cohort study
CONCLUSIONS: Kidney injury occurred in more than half of the patients with CHF during hospitalization. The independent risk factors for kidney injury in the CHF patients included sex (male), hypertension, and stroke. Kidney injury was positively correlated with age and serum potassium, and negatively correlated with serum albumin, hemoglobin concentration, LVEF, and ARB application.PMID:37559657 | PMC:PMC10407521 | DOI:10.21037/jtd-23-1016
Source: Journal of Thoracic Disease - August 10, 2023 Category: Respiratory Medicine Authors: Xiaoran Shen Hongliang Guo Guglielmo Mantica Hui Yuan Source Type: research

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