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Condition: Subarachnoid Hemorrhage
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Total 3336 results found since Jan 2013.
Recommendations From the International Stroke Genetics Consortium, Part 1: Standardized Phenotypic Data Collection Comments and Opinions
Source: Stroke - December 22, 2014 Category: Neurology Authors: Majersik, J. J., Cole, J. W., Golledge, J., Rost, N. S., Chan, Y.-F. Y., Gurol, M. E., Lindgren, A. G., Woo, D., Fernandez-Cadenas, I., Chen, D. T., Thijs, V., Worrall, B. B., Kamal, A., Bentley, P., Wardlaw, J. M., Ruigrok, Y. M., Battey, T. W. K., Schmi Tags: Acute Cerebral Hemorrhage, Acute Cerebral Infarction, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Genetics of Stroke, Risk Factors for Stroke Comments and Opinions Source Type: research
Numerous Fusiform and Saccular Cerebral Aneurysms in Central Nervous System Lupus Presenting with Ischemic Stroke
We report a patient with an active SLE flare who presented with a recurrent ischemic stroke and was found to have numerous unruptured fusiform and saccular aneurysms in multiple vascular territories. He was treated with high-dose steroid and rituximab along with aspirin and blood pressure control for stroke prevention.
Source: Journal of Stroke and Cerebrovascular Diseases - May 4, 2017 Category: Neurology Authors: Shahram Majidi, Christopher R. Leon Guerrero, Shreya Gandhy, Kathleen M. Burger, Dimitri Sigounas Tags: Case Studies Source Type: research
The HOPES Registry – Houston Methodist Hospital Outcomes-based Prospective Endpoints in Stroke
We present a single institution registry with the novel feature of 90-day outcome assessments on all hospitalized acute stroke patients, inclusive of every patient with a primary discharge diagnosis of transient ischemic attack (TIA), acute ischemic stroke (AIS), nontraumatic subarachnoid hemorrhage (SAH), and intracerebral hemorrhage (ICH).
Source: Journal of Stroke and Cerebrovascular Diseases - July 30, 2018 Category: Neurology Authors: Rajan Gadhia, David McCane, Jason Lee, Ken Chyuan Ling, Kevin Jiang, David Chiu Source Type: research
Study: Racial, ethnic differences in outcomes following stroke known as subarachnoid hemorrhage
Race or ethnicity can be a significant clue in the United States as to who will survive a kind of stroke known as a subarachnoid hemorrhage and who will be discharged to institutional care, a new study has found. Compared to Caucasians, Asian/Pacific Islander patients were more likely and Hispanic patients less likely to die of a subarachnoid hemorrhage, or SAH, while in the hospital. African-American patients were more likely than Caucasians to require institutional care following discharge from the hospital, although their risk of death while in the hospital was similar...
Source: Health News from Medical News Today - September 13, 2013 Category: Consumer Health News Tags: Stroke Source Type: news
Endovascular and surgical options for ruptured middle cerebral artery aneurysms: review of the literature.
Authors: Santiago-Dieppa DR, Pannell JS, Khalessi AA
Abstract
Middle cerebral artery (MCA) aneurysms are common entities, and those of the bifurcation are the most frequently encountered sublocation of MCA aneurysm. MCA bifurcation (MBIF) aneurysms commonly present with subarachnoid hemorrhage (SAH), are devastating, and are often lethal. At the present time, the treatment of ruptured MBIF aneurysms entails either endovascular or open microneurosurgical methods to permanently secure the aneurysm(s). The purpose of this report is to review the current available data regarding the relative superiority of endovascular...
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research
Brain injury after transient global cerebral ischemia and subarachnoid hemorrhage.
Authors: Sehba FA, Pluta RM, Macdonald RL
PMID: 24327930 [PubMed]
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research
Acute microvascular changes after subarachnoid hemorrhage and transient global cerebral ischemia.
Authors: Tso MK, Macdonald RL
Abstract
Subarachnoid hemorrhage and transient global cerebral ischemia result in similar pathophysiological changes in the cerebral microcirculation. These changes include microvascular constriction, increased leukocyte-endothelial interactions, blood brain barrier disruption, and microthrombus formation. This paper will look at various animal and preclinical studies that investigate these various microvascular changes, perhaps providing insight in how these microvessels can be a therapeutic target in both subarachnoid hemorrhage and transient global cerebral ischemia.
PMID: 23589781 [PubMed]
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research
Early brain injury: a common mechanism in subarachnoid hemorrhage and global cerebral ischemia.
Authors: Sabri M, Lass E, Macdonald RL
Abstract
Early brain injury (EBI) has become an area of extreme interest in the recent years and seems to be a common denominator in the pathophysiology of global transient ischemia and subarachnoid hemorrhage (SAH). In this paper, we highlight the importance of cerebral hypoperfusion and other mechanisms that occur in tandem in both pathologies and underline their possible roles in triggering brain injury after hemorrhagic or ischemic strokes.
PMID: 23533958 [PubMed]
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research
Clinical trials in cardiac arrest and subarachnoid hemorrhage: lessons from the past and ideas for the future.
Conclusions. Clinical trials in SAH assessing acute brain injury are warranted and successful interventions identified by the cardiac arrest literature may be reasonable targets of the study.
PMID: 23533956 [PubMed]
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research
CSF and Serum Biomarkers Focusing on Cerebral Vasospasm and Ischemia after Subarachnoid Hemorrhage.
Authors: Jung CS, Lange B, Zimmermann M, Seifert V
Abstract
Delayed cerebral vasospasm (CVS) and delayed cerebral ischemia (DCI) remain severe complications after subarachnoid hemorrhage (SAH). Although focal changes in cerebral metabolism indicating ischemia are detectable by microdialysis, routinely used biomarkers are missing. We therefore sought to evaluate a panel of possible global markers in serum and cerebrospinal fluid (CSF) of patients after SAH. CSF and serum of SAH patients were analyzed retrospectively. In CSF, levels of inhibitory, excitatory, and structural amino acids were detected by high-performan...
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research
Calcium and potassium channels in experimental subarachnoid hemorrhage and transient global ischemia.
Authors: Kamp MA, Dibué M, Schneider T, Steiger HJ, Hänggi D
Abstract
Healthy cerebrovascular myocytes express members of several different ion channel families which regulate resting membrane potential, vascular diameter, and vascular tone and are involved in cerebral autoregulation. In animal models, in response to subarachnoid blood, a dynamic transition of ion channel expression and function is initiated, with acute and long-term effects differing from each other. Initial hypoperfusion after exposure of cerebral vessels to oxyhemoglobin correlates with a suppression of voltage-gated potassium channel activity...
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research
Frontal Networks Associated With Command Following After Hemorrhagic Stroke Clinical Sciences
Conclusions—
Resting-state functional MRI and electroencephalography coherence data support a model in which multiple, chiefly frontal networks are required for command following. Loss of DMN anticorrelation with task-positive network may reflect a loss of inhibitory control of the DMN by motor-executive regions. Frontal networks should thus be a target for future investigations into the mechanism of responsiveness in the intensive care unit environment.
Source: Stroke - December 22, 2014 Category: Neurology Authors: Mikell, C. B., Banks, G. P., Frey, H.-P., Youngerman, B. E., Nelp, T. B., Karas, P. J., Chan, A. K., Voss, H. U., Connolly, E. S., Claassen, J. Tags: Acute Cerebral Hemorrhage, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Other imaging Clinical Sciences Source Type: research
Influence of Antiplatelet Drugs on the Outcome of Subarachnoid Hemorrhage Differs with Age
The aim of this study was to examine the risk factor profiles and functional outcomes of subarachnoid hemorrhage (SAH) in different age groups, focusing on the effect of antiplatelet drugs when used before stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - July 20, 2015 Category: Neurology Authors: Yuji Kato, Takeshi Hayashi, Norio Tanahashi, Shotai Kobayashi, the Japan Standard Stroke Registry Study Group Source Type: research
Predictive Factors for Rebleeding After Aneurysmal Subarachnoid Hemorrhage: Rebleeding Aneurysmal Subarachnoid Hemorrhage Study Clinical Sciences
Conclusions—
In our opinion, timing of treatment of aSAH patients, especially those with an modified Fisher grade of 3 or 4 in a good clinical condition, should be reconsidered. These aSAH patients might be regarded a medical emergency, requiring aneurysm repair as soon as possible. In this respect, our findings should provoke the debate on timing of aneurysm repair, especially in patients considered to be at high risk for rebleeding.
Source: Stroke - July 27, 2015 Category: Neurology Authors: van Donkelaar, C. E., Bakker, N. A., Veeger, N. J. G. M., Uyttenboogaart, M., Metzemaekers, J. D. M., Luijckx, G.-J., Groen, R. J. M., van Dijk, J. M. C. Tags: Acute Cerebral Hemorrhage, Cerebral Aneurysm, AVM, & Subarachnoid hemorrhage, Emergency treatment of Stroke, Aneurysm, AVM, hematoma Clinical Sciences Source Type: research
Therapeutically Targeting Tumor Necrosis Factor-{alpha}/Sphingosine-1-Phosphate Signaling Corrects Myogenic Reactivity in Subarachnoid Hemorrhage Basic Sciences
Conclusions—
Vascular smooth muscle cell TNFα and sphingosine-1-phosphate signaling significantly enhance cerebral artery tone in SAH; anti-TNFα and anti–sphingosine-1-phosphate treatment may significantly improve clinical outcome.
Source: Stroke - July 27, 2015 Category: Neurology Authors: Yagi, K., Lidington, D., Wan, H., Fares, J. C., Meissner, A., Sumiyoshi, M., Ai, J., Foltz, W. D., Nedospasov, S. A., Offermanns, S., Nagahiro, S., Macdonald, R. L., Bolz, S.-S. Tags: Animal models of human disease, Acute Cerebral Hemorrhage, Brain Circulation and Metabolism, Other Stroke Treatment - Medical, Other Vascular biology Basic Sciences Source Type: research
