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Source: Journal of Neurosurgery
Condition: Hemorrhagic Stroke

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Total 231 results found since Jan 2013.

Effect of endovascular treatment within 6 hours for acute basilar artery occlusion
CONCLUSIONS: Based on the study design, patients with acute BAO who received EVT within 6 hours were associated with improved favorable outcome and decreased deaths compared with patients who received SMT. Predictors of desirable outcome in patients undergoing EVT included lower age, lower baseline National Institutes of Health Stroke Scale score, higher baseline posterior circulation Alberta Stroke Program Early CT Score, absence of diabetes mellitus, and modified Thrombolysis in Cerebral Infarction scores 2b-3.PMID:35623368 | DOI:10.3171/2022.4.JNS22355
Source: Journal of Neurosurgery - May 27, 2022 Category: Neurosurgery Authors: Jie Yang Fengli Li Zhongming Qiu Yan Wang Jun Luo Youlin Wu Guoyong Zeng Yue Wan Shuai Liu Chengsong Yue Jiaxing Song Weidong Luo Chang Liu Linyu Li Ruidi Sun Jiacheng Huang Hongfei Sang Chenhao Zhao Qingwu Yang Wenjie Zi Source Type: research

Time course of recovery following poor-grade SAH: the incidence of delayed improvement and implications for SAH outcome study design.
Conclusions A substantial minority of poor-grade SAH patients will experience delayed recovery beyond the point at which most studies assess outcome. Younger patients, those presenting in better clinical condition, and those without CT evidence of large or eloquent stroke demonstrated the highest capacity for delayed recovery. PMID: 23724983 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - May 31, 2013 Category: Neurosurgery Authors: Wilson DA, Nakaji P, Albuquerque FC, McDougall CG, Zabramski JM, Spetzler RF Tags: J Neurosurg Source Type: research

Endovascular treatment for emergent large vessel occlusion due to severe intracranial atherosclerotic stenosis.
CONCLUSIONS Both intracranial angioplasty/stenting and intraarterial infusion of a glycoprotein IIb/IIIa inhibitor are effective and safe in the treatment of underlying severe ICAS in acute stroke patients with ELVO. In addition, a lack of a history of stroke/TIA was the only independent predictor of good outcome after endovascular therapy in such patients. PMID: 29932374 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - June 22, 2018 Category: Neurosurgery Authors: Kang DH, Yoon W, Kim SK, Baek BH, Lee YY, Kim YW, Kim YS, Hwang YH, Kim JT, Park MS Tags: J Neurosurg Source Type: research

Early reperfusion and clinical outcomes in patients with M2 occlusion: pooled analysis of the PROACT II, IMS, and IMS II studies.
Conclusions A positive correlation between successful early reperfusion and clinical outcome could not be demonstrated for patients with M2 occlusion. Irrespective of reperfusion status, such patients have better outcomes than those with more proximal occlusions, with more than 50% achieving functional independence at 3 months. PMID: 25259569 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - September 26, 2014 Category: Neurosurgery Authors: Rahme R, Yeatts SD, Abruzzo TA, Jimenez L, Fan L, Tomsick TA, Ringer AJ, Furlan AJ, Broderick JP, Khatri P Tags: J Neurosurg Source Type: research

Safety and efficacy of the Pipeline embolization device for treatment of intracranial aneurysms: a pooled analysis of 3 large studies.
CONCLUSIONS Endovascular treatment of intracranial aneurysms with the PED is safe and effective. Angiographic occlusion rates progressed with follow-up. Rates of stroke, hemorrhage, morbidity and mortality, and retreatment were low, especially given the fact that the aneurysms treated were generally large and wide necked. PMID: 27791519 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - October 27, 2016 Category: Neurosurgery Authors: Kallmes DF, Brinjikji W, Cekirge S, Fiorella D, Hanel RA, Jabbour P, Lopes D, Lylyk P, McDougall CG, Siddiqui A Tags: J Neurosurg Source Type: research

Intravenous infusion of mesenchymal stem cells inhibits intracranial hemorrhage after recombinant tissue plasminogen activator therapy for transient middle cerebral artery occlusion in rats.
CONCLUSIONS Infused MSCs may inhibit endothelial dysfunction to suppress hemorrhagic events and facilitate functional outcome. Combined therapy of infused MSCs after rtPA therapy facilitated early behavioral recovery. PMID: 28059661 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - January 5, 2017 Category: Neurosurgery Authors: Nakazaki M, Sasaki M, Kataoka-Sasaki Y, Oka S, Namioka T, Namioka A, Onodera R, Suzuki J, Sasaki Y, Nagahama H, Mikami T, Wanibuchi M, Kocsis JD, Honmou O Tags: J Neurosurg Source Type: research

Neutrophil-to-lymphocyte ratio as an independent predictor for unfavorable functional outcome in aneurysmal subarachnoid hemorrhage.
CONCLUSIONSAmong aSAH patients, NLR represents an independent parameter associated with unfavorable functional outcome. Whether the impact of NLR on functional outcome is related to preexisting comorbidities or represents independent causal relationships in the context of stroke-associated immunosuppression should be investigated in future studies. PMID: 30717052 [PubMed - as supplied by publisher]
Source: Journal of Neurosurgery - February 1, 2019 Category: Neurosurgery Authors: Giede-Jeppe A, Reichl J, Sprügel MI, Lücking H, Hoelter P, Eyüpoglu IY, Kuramatsu JB, Huttner HB, Gerner ST Tags: J Neurosurg Source Type: research

Multimodal cerebral arteriovenous malformation treatment: a 12-year experience and comparison of key outcomes to ARUBA.
CONCLUSIONS: This multimodal approach to the selection and treatment of patients with brain AVMs yields good clinical outcomes with key safety endpoints (stroke, death, and mRS score 0-1) better than the ARUBA intervention arm and similar to the ARUBA medical arm at 5 years of follow-up. Results compare favorably to natural history cohorts at longer follow-up times. This suggests that tertiary care centers with integrated programs, expertise in patient selection, and individualized treatment approaches may allow for better clinical outcomes than reported in ARUBA. It supports current registry studies and merits considerati...
Source: Journal of Neurosurgery - October 31, 2019 Category: Neurosurgery Authors: Pulli B, Chapman PH, Ogilvy CS, Patel AB, Stapleton CJ, Leslie-Mazwi TM, Hirsch JA, Carter BS, Rabinov JD Tags: J Neurosurg Source Type: research

Periprocedural cerebrovascular complications and 30-day outcomes of endovascular treatment for intracranial vertebral artery dissecting aneurysms
CONCLUSIONS: Hyperlipidemia, IS history, and SAH were independent predictors for overall periprocedural cerebrovascular complications of endovascular treatment for IVADAs, but aneurysmal height was an independent protective factor. SAH and preprocedural mRS score > 2 were independent risk factors for perforator occlusion stroke. Preprocedural mRS score > 2 and periprocedural complications were independent risk factors for 30-day unfavorable clinical outcomes.PMID:36401540 | DOI:10.3171/2022.10.JNS221953
Source: Journal of Neurosurgery - November 19, 2022 Category: Neurosurgery Authors: Jiangli Han Fei Liu Jigang Chen Xin Tong Mingyang Han Fei Peng Hao Niu Lang Liu Aihua Liu Source Type: research