Multimodal cerebral arteriovenous malformation treatment: a 12-year experience and comparison of key outcomes to ARUBA.

CONCLUSIONS: This multimodal approach to the selection and treatment of patients with brain AVMs yields good clinical outcomes with key safety endpoints (stroke, death, and mRS score 0-1) better than the ARUBA intervention arm and similar to the ARUBA medical arm at 5 years of follow-up. Results compare favorably to natural history cohorts at longer follow-up times. This suggests that tertiary care centers with integrated programs, expertise in patient selection, and individualized treatment approaches may allow for better clinical outcomes than reported in ARUBA. It supports current registry studies and merits consideration of future randomized controlled trials in patients with brain AVMs. PMID: 31675689 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31675689?dopt=Abstract

Source: Journal of Neurosurgery - October 31, 2019 Category: Neurosurgery Authors: Pulli B, Chapman PH, Ogilvy CS, Patel AB, Stapleton CJ, Leslie-Mazwi TM, Hirsch JA, Carter BS, Rabinov JD Tags: J Neurosurg Source Type: research