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Condition: Hemorrhagic Stroke
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Total 80 results found since Jan 2013.

External validation of the SEDAN score: The real world practice of a single center
Conclusions: The SEDAN score was practical to use and predictive in Thai population. Each parameter of the SEDAN score was an independent risk factor for sICH after treatment with i.v. rt-PA.
Source: Annals of Indian Academy of Neurology - May 8, 2015 Category: Neurology Authors: Sombat MuengtaweepongsaPornpoj Prapa-AnantachaiPornpatr A DharmasarojaPattarawit RukkulPornchai Yodvisitsak Source Type: research

A Mobile Application for Predicting 90-day Outcomes after IV Thrombolysis in Ischemic Stroke (P3.069)
CONCLUSIONS: We evaluated the ability of our score to predict 90-day outcomes and developed an iOS application based on results. Our mobile application brings a unique opportunity to optimize rT-PA treatment decisions for acute ischemic stroke patients.Disclosure: Dr. Nystrom has nothing to disclose. Dr. Asuzu has nothing to disclose. Dr. Amin has nothing to disclose. Dr. Schindler has nothing to disclose. Dr. Wira has nothing to disclose. Dr. Greer has received personal compensation in an editorial capacity for Seminars in Neurology. Dr. Chi has nothing to disclose. Dr. Halliday has nothing to disclose. Dr. Sheth has rece...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Nystrom, K., Asuzu, D., Amin, H., Schindler, J., Wira, C., Greer, D., Chi, N. F., Halliday, J., Sheth, K. Tags: Cerebrovascular Disease and Interventional Neurology: Ischemic Stroke Outcome Source Type: research

Rate of Peri-Hematomal Edema Expansion Predicts Outcome after Intracerebral Hemorrhage (S39.005)
CONCLUSIONS: PHE expansion rate predicts outcome in ICH and may represent a novel therapeutic target. Study Supported by: NIH-K12-NS049453 (LB); NINDS K23NS076597 (WTK); Leon Rosenberg, MD Medical Student Research Fund in Genetics, Yale School of Medicine; 2014 Student Scholarship in Cerebrovascular Disease and Stroke, AHA Stroke Council (SU)Disclosure: Dr. Urday has nothing to disclose. Dr. Beslow has nothing to disclose. Dr. Goldstein has nothing to disclose. Dr. Dai has nothing to disclose. Dr. Zhang has nothing to disclose. Dr. Vashkevich has received research support from the National Institutes of Health. Dr. Ayres h...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Urday, S., Beslow, L., Goldstein, D., Dai, F., Zhang, F., Vashkevich, A., Ayres, A., Battey, T., Simard, M., Rosand, J., Kimberly, W., Sheth, K. Tags: Cerebrovascular Disease and Interventional Neurology: Intracerebral Hemorrhage Source Type: research

Comparison of On-hour vs Off-hour Patient Cohorts at a Primary Stroke Center: Onset-To-Treatment Duration and Clinical Outcomes after IV Thrombolysis (S21.005)
CONCLUSIONS: We found no significant differences in OTT durations, stroke severity, or stroke outcomes between patients whose symptoms originated during on-hours vs off-hours. This represents progress in emergency response, recognition and acute stroke care delivered by our Emergency Department staff and acute stroke team on a 24 hour basis and likely reflects nationwide efforts to provide consistent care for acute stroke patients.Disclosure: Dr. Nystrom has nothing to disclose. Dr. Asuzu has nothing to disclose. Dr. Amin has nothing to disclose. Dr. Schindler has nothing to disclose. Dr. Wira has nothing to disclose. Dr. ...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Nystrom, K., Asuzu, D., Amin, H., Schindler, J., Wira, C., Greer, D., Chi, N. F., Halliday, J., Sheth, K. Tags: Cerebrovascular Disease and Interventional Neurology: Prehospital and Acute Ischemic Stroke Treatment Source Type: research

Transitions of care for stroke and TIA
ConclusionHospital length of stay, age, insurance status, discharge disposition, comorbidities, and readmission rates were identified as important elements affecting TOC for stroke and TIA. Information from patient surveys indicated that emotional health, follow‐up with care providers, stroke education, and point of contact are important elements during the transition periods after stroke and TIA. Implications for practiceBoth providers and patients should inform the development of a comprehensive TOC program that spans in‐hospital to multiple care settings, including the home, which is essential. The advanced practice...
Source: Journal of the American Academy of Nurse Practitioners - March 4, 2015 Category: Nursing Authors: Helena N. Haynes, Matthew J. Gallek, Kate G. Sheppard, Kendra W. Drake, Leslie S. Ritter Tags: QUALITY IMPROVEMENT Source Type: research

Contribution of reactive oxygen species to CAA Neuroscience
Cerebral amyloid angiopathy (CAA) is characterized by deposition of amyloid β peptide (Aβ) within walls of cerebral arteries and is an important cause of intracerebral hemorrhage, ischemic stroke, and cognitive dysfunction in elderly patients with and without Alzheimer’s Disease (AD). NADPH oxidase-derived oxidative stress plays a key role in soluble...
Source: Proceedings of the National Academy of Sciences - February 24, 2015 Category: Science Authors: Han, B. H., Zhou, M.-l., Johnson, A. W., Singh, I., Liao, F., Vellimana, A. K., Nelson, J. W., Milner, E., Cirrito, J. R., Basak, J., Yoo, M., Dietrich, H. H., Holtzman, D. M., Zipfel, G. J. Tags: PNAS Plus Source Type: research

Pattern and risk factors of stroke in the young among stroke patients admitted in medical college hospital, Thiruvananthapuram
Conclusion: In all, 15% of total stroke occurred in young adults <50 years. The proportion of hemorrhagic stroke in young adults is higher than in elderly. Atrial fibrillation is identified as an independent risk factor of stroke in the young. Compared with stroke in elderly alcohol use, smoking, hyperlipidemia, and cardiac diseases, which are known risk factors, are higher in young stroke.
Source: Annals of Indian Academy of Neurology - February 10, 2015 Category: Neurology Authors: Praveen Prasannakumar SubhaSabarinadh Muraleedharan Pillai GeethakumariMohan AthiraZinia Thajudeen Nujum Source Type: research

Notch initiates AV shunts from capillaries Medical Sciences
Arteriovenous (AV) malformation (AVM) is a devastating condition characterized by focal lesions of enlarged, tangled vessels that shunt blood from arteries directly to veins. AVMs can form anywhere in the body and can cause debilitating ischemia and life-threatening hemorrhagic stroke. The mechanisms that underlie AVM formation remain poorly understood. Here,...
Source: Proceedings of the National Academy of Sciences - December 16, 2014 Category: Science Authors: Murphy, P. A., Kim, T. N., Huang, L., Nielsen, C. M., Lawton, M. T., Adams, R. H., Schaffer, C. B., Wang, R. A. Tags: Biological Sciences Source Type: research

Crohns disease with central nervous system vasculitis causing subarachnoid hemorrhage due to aneurysm and cerebral ischemic stroke
We report a 39-year-old male who presented with headache, vomiting, and left-sided weakness in the known case of CD. Cross-sectional imaging (computed tomography and magnetic resonance imaging,) showed right gangliocapsular acute infarct with supraclinoid cistern subarachnoid hemorrhage (SAH). Cerebral digital substraction angiography (DSA) showed dilatation and narrowing of right distal internal carotid artery (ICA). Left ICA was chronically occluded. His inflammatory markers were significantly raised. Imaging features are suggestive of cerebral vasculitis. Arterial and venous infarcts due to thrombosis are known in CD. O...
Source: Annals of Indian Academy of Neurology - November 5, 2014 Category: Neurology Authors: Shaileshkumar S GargePooja D VyasPranav D ModiSharad Ghatge Source Type: research

Intravenous thrombolysis in a patient with left atrial myxoma with acute ischemic stroke
In this report we describe our experience of IVT in atrial myxoma patient with ischemic stroke and review the relevant literature.
Source: Annals of Indian Academy of Neurology - November 5, 2014 Category: Neurology Authors: Girish Baburao KulkarniRavi YadavVeerendrakumar MustareSailesh Modi Source Type: research

Varied presentations of moyamoya disease in a tertiary care hospital of north-east India
Conclusion: Owing to its low incidence in India, moyamoya disease is easily overlooked as a possible diagnosis. However, because of its progressive nature, it is imperative to diagnose this disease early and offer surgical treatment to the patients.
Source: Annals of Indian Academy of Neurology - August 12, 2014 Category: Neurology Authors: Papori BorahVikas SharmaLakshya Jyoti BasumataryMarami DasMunindra GoswamiAshok K Kayal Source Type: research

Dabigatran etexilate: An alternative to warfarin for patients with nonvalvular atrial fibrillation
ConclusionsSignificant evidence from the PETRO and RE‐LY trials and postmarketing analyses of dabigatran etexilate indicate that this direct thrombin inhibitor is as efficacious as warfarin in ischemic stroke prevention. In fact, the studies found that patients taking dabigatran etexilate had fewer incidences of ischemic stroke and intracranial hemorrhage than those taking warfarin. Risk for major gastrointestinal bleeding appears to be higher than that for warfarin. Implications for practicePatients taking dabigatran etexilate do not require blood work to assess international normalized ratio (INR) levels. Because this ...
Source: Journal of the American Academy of Nurse Practitioners - July 25, 2014 Category: Nursing Authors: Katie A. Scott, Karen A. Amirehsani Tags: CLINICAL PRACTICE Source Type: research

HAT Score Outperforms 7 Other Hemorrhagic Transformation Scores in Ischemic Stroke Patients Treated with Thrombolysis (P3.109)
Conclusions: HAT score yielded the highest odds ratio among the 4 scores that accurately predicted sICH in our independent dataset. HAT score also had low computational complexity compared to other scores. Our results demonstrate the potential utility of the HAT score as a predictor of adverse clinical outcome for acute ischemic stroke patients undergoing IV thrombolytic therapy.Disclosure: Dr. Asuzu has nothing to disclose. Dr. Nystrom has nothing to disclose. Dr. Halliday has nothing to disclose. Dr. Wira has nothing to disclose. Dr. Greer has nothing to disclose. Dr. Schindler has nothing to disclose. Dr. Sheth has rece...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Asuzu, D., Nystrom, K., Halliday, J., Wira, C., Greer, D., Schindler, J., Sheth, K. Tags: Cerebrovascular Disease and Interventional Neurology: t-PA Source Type: research

The Discharge Modified Rankin Scale Score Correlates with Established Hemorrhagic Transformation Scores in Ischemic Stroke Patients Treated with Thrombolysis (P7.118)
Conclusions: Discharge MRS scores showed robust agreement with at least 3 HT scores known to predict long-term functional outcomes after IV rt-PA therapy. Therefore, readily available discharge MRS scores may be useful indicator of patients requiring closer follow-up after IV rt-PA therapy.Disclosure: Dr. Asuzu has nothing to disclose. Dr. Nystrom has nothing to disclose. Dr. Halliday has nothing to disclose. Dr. Wira has nothing to disclose. Dr. Greer has nothing to disclose. Dr. Pritchard has nothing to disclose. Dr. Schindler has nothing to disclose. Dr. Sheth has received research support from the American Academy of N...
Source: Neurology - April 9, 2014 Category: Neurology Authors: Asuzu, D., Nystrom, K., Halliday, J., Wira, C., Greer, D., Pritchard, D., Schindler, J., Sheth, K. Tags: Cerebrovascular Disease and Interventional Neurology: Issues in Acute Stroke Treatment Source Type: research

Hyponatremia in stroke
Conclusion: Incidence of hyponatremia in our study population was 35%. In patients of hyponatremia 67% were having SIADH and 33% were having CSWS. Overall hyponatremia affected the outcome of stroke especially when caused by CSWS. Therefore close monitoring of serum sodium must be done in all patients who are admitted with stroke and efforts must be made to determine the cause of hyponatremia, in order to properly manage such patients thereby decreasing the mortality rate.
Source: Annals of Indian Academy of Neurology - March 12, 2014 Category: Neurology Authors: Sheikh SaleemIrfan YousufAzhara GulSatish GuptaSawan Verma Source Type: research