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Sudden unexpected death in schizophrenia: Autopsy findings in psychiatric inpatients
In conclusion, sudden cardiac death occurs at a 0.8% rate in a psychiatric hospital, well above general population rates. Autopsy findings indicate that sudden death in schizophrenia is caused by structural cardiovascular, respiratory and neurological abnormalities, with most cases due to acute myocardial infarction. Early recognition and treatment of coronary artery disease must become a clinical priority for all adults with schizophrenia.
Source: Schizophrenia Research - April 7, 2014 Category: Psychiatry Authors: Petru Ifteni, Christoph U. Correll, Victoria Burtea, John M. Kane, Peter Manu Tags: Clinical Studies Source Type: research

Pulmonary Arteriovenous Malformations and Embolic Complications in Patients With Hereditary Hemorrhagic Telangiectasia.
We describe baseline characteristics of HHT and compare the prevalence of embolic complications in patients with significant PAVM compared to patients without significant PAVM. One hundred and eight consecutive patients were included. Significant PAVM was defined as: contrast echocardiography grade 2 or greater; bilateral PAVM or feeding artery bigger than 3mm; or previous PAVM treatment. Primary composite outcome was defined as: cerebrovascular accident, cerebral abscess or peripheral embolism. 20% of participants had embolic complications, the most frequent one was stroke. Embolic complications were associated with signi...
Source: Archivos de Bronconeumologia - March 11, 2014 Category: Respiratory Medicine Authors: Angriman F, Ferreyro BL, Wainstein EJ, Serra MM Tags: Arch Bronconeumol Source Type: research

Improving the one-year mortality of stroke patients: an 18-year observation in a teaching hospital.
This study determined the one-year survival rate and prognostic factors of hospitalized hemorrhagic and ischemic stroke patients from 1991 to 2008 in a teaching hospital in Taiwan. We also evaluated the improvements in the one-year mortality after stroke during an 18-year study period. Patients admitted for cerebral hemorrhage (n = 3,678) and cerebral infarction (n = 16,010), identified from an in-patient electronic database, were linked to the National Death Registry of Taiwan. Actuarial analysis was used to determine the one-year survival rates, and Cox proportional hazard regression model was used to investigate the pre...
Source: The Tohoku Journal of Experimental Medicine - February 8, 2014 Category: Research Authors: Chen HF, Li CY, Lee SP, Kwok YT, Chu YT Tags: Tohoku J Exp Med Source Type: research

Pineal Calcification Is Associated with Symptomatic Cerebral Infarction
Conclusions: Pineal calcification may be a potential new contributor to cerebral infarction.
Source: Journal of Stroke and Cerebrovascular Diseases - February 22, 2013 Category: Neurology Authors: Amnat Kitkhuandee, Kittisak Sawanyawisuth, Nutjaree Pratheepawanit Johns, Jaturat Kanpittaya, Jeffrey Johns Tags: Original Articles Source Type: research

Clinico-Radiological Profile of Strokes in Kashmir Valley, North-West India: A Study from a University Hospital (P03.172)
CONCLUSIONS: Intracerebral hemorrhage was the commonest stroke-type observed in Kashmir accounting for close to two third of strokes with male preponderance.Disclosure: Dr. Shah has nothing to disclose. Dr. Bardi has nothing to disclose. Dr. Dar has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Shah, P., Bardi, G., Dar, A. Tags: P03 Cerebrovascular Disease III Source Type: research

Increased Hemoglobin A1c Level Is Associated with Decreased Hematoma Volume in Patients with Spontaneous Intracerebral Hemorrhage (P03.176)
CONCLUSIONS: Our data showed inverse correlation between HbA1c levels and BHV. This contradiction may suggest that acute hyperglycemia in response to acute stress is the effect rather than cause of severe ICH. Further studies to determine if increased HbA1c levels lead to the early activation of clotting factors in ICH patients, or increased HbA1c levels lead to changes in the structure of the vessel wall is warranted.Disclosure: Dr. Mehta has nothing to disclose. Dr. Dass has nothing to disclose. Dr. Moussavi has nothing to disclose. Dr. Sodhi has nothing to disclose. Dr. Nizam has nothing to disclose. Dr. Korya has nothi...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Mehta, S., Dass, P., Moussavi, M., Sodhi, R., Nizam, A., Korya, D., Dababneh, H., Ibrahim, M., Kirmani, J. Tags: P03 Cerebrovascular Disease III Source Type: research

Rate of Utilization and Determination of Withdrawal of Care among Acute Ischemic Stroke Patient Treated with Thrombolytics (P02.002)
CONCLUSIONS: Our results identify several individual and institution related factors that determine the use of "withdrawal of care" among thrombolytic treated ischemic stroke patients. The excessively high mortality and resource utilization mandates a more evidence based policy for "withdrawal of care" in these patients.Disclosure: Dr. Suri has nothing to disclose. Dr. Adil has nothing to disclose. Dr. Gilani has nothing to disclose. Dr. ATACH Investigators has nothing to disclose.
Source: Neurology - February 14, 2013 Category: Neurology Authors: Suri, M. F., Adil, M., Gilani, W., Qureshi, A. Tags: P02 Ethics, Pain, and Palliative Care Source Type: research

Predictive Risk Factors of In-Hospital Mortality Following Acute Stroke in the United States: Data from the Nationwide Inpatient Database, 2006-2010 (P02.015)
CONCLUSIONS: The rate of in-hospital mortality is relatively high following acute stroke (8.42%). We identified multiple risk factors of in-hospital mortality in acute stroke patients. The strongest risk factor is the type stroke (hemorrhagic). The present finding suggests that patients at increased risk of mortality can be identified and additional treatment for prevention might be warranted.Disclosure: Dr. Naderi has nothing to disclose. Dr. Abcede has nothing to disclose. Dr. Al-Khoury has nothing to disclose. Dr. Mozaffar has received personal compensation for activities with California Stem Cell Inc., NuFactor, Cresce...
Source: Neurology - February 14, 2013 Category: Neurology Authors: Naderi, N., Abcede, H., Al-Khoury, L., Mozaffar, T., Jain, V. Tags: P02 Cerebrovascular Disease II Source Type: research

Thrombolysis and Outcome of Young Stroke Patients Over the Last Decade: Insights From the Nationwide Inpatient Sample
Background: A recent study found a trend toward increasing hospitalizations for acute ischemic stroke (AIS) among young adults, raising concern for this subgroup. In the present study, we evaluated trends of use of thrombolysis and outcome among young adults (19-44 years of age) with AIS using a nationally representative administrative database.Methods: Discharge data were obtained from Nationwide Inpatient Sample between 2001 and 2009. Hospitalizations with a discharge diagnosis of AIS for patients 19 to 44 years of age were included. Use of thrombolysis was determined within this subset. The Cochran–Armitage test was u...
Source: Journal of Stroke and Cerebrovascular Diseases - June 11, 2012 Category: Neurology Authors: Amit Kansara, Seemant Chaturvedi, Pratik Bhattacharya Tags: Original Articles Source Type: research

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