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Peripheral axonal excitability in hemiplegia related to subacute stroke.
CONCLUSION: The lower motor neurons were affected at the level of axonal channels as a result of upper motor neuron lesion. It can be due to dying back neuropathy, homeostasis and neurovascular regulation changes in the axonal environment, activity dependant plastic changes, loss of drive coming from the central nervous system or the combination of these factors. PMID: 32682362 [PubMed - as supplied by publisher]
Source: Turkish Journal of Medical Sciences - July 20, 2020 Category: General Medicine Tags: Turk J Med Sci Source Type: research

Ankle clonus
We present a video case of impressive left ankle clonus in a patient with old right middle cerebral artery stroke. Clonus is a series of involuntary, rhythmic, muscular contractions, and relaxations. It may be caused by interruption of the upper motor neuron fibers such as stroke, multiple sclerosis, or by metabolic alterations such as severe hepatic failure or serotonin syndrome. We present a video case of impressive left ankle clonus in a patient with old right middle cerebral artery stroke.
Source: Clinical Case Reports - April 9, 2015 Category: Journals (General) Authors: Shoaib Bilal Fareedy, Ranjan Pathak Tags: Clinical Video Source Type: research

Asynchronization in Changes of Electrophysiology and Pathology of Spinal Cord Motor Neurons in Rats Following Middle Cerebral Artery Occlusion.
CONCLUSIONS: Both electrophysiological and pathological studies showed transsynaptic degeneration after stroke. This study identified the asynchronization in changes of electrophysiology and pathology. The abnormal physiological changes and function impairment can be detected in the early stage and recovered quickly, while the pathological loss of motor neuron can be detected only in a later stage. PMID: 26521791 [PubMed - in process]
Source: Chinese Medical Journal - November 1, 2015 Category: Journals (General) Authors: Lin N, Liu MS, Fan SY, Guan YZ, Cui LY Tags: Chin Med J (Engl) Source Type: research

Burden of neurological diseases in Asia from 1990 to 2019: a systematic analysis using the Global Burden of Disease Study data
Conclusions This study demonstrated the burden of neurological diseases in Asia. To reduce the burden of neurological diseases, strategies suitable for each country’s real healthcare needs and challenges are needed; this study can serve as the cornerstone of these strategies.
Source: BMJ Open - September 7, 2022 Category: General Medicine Authors: Kang, S., Eum, S., Chang, Y., Koyanagi, A., Jacob, L., Smith, L., Shin, J. I., Song, T.-J. Tags: Open access, Epidemiology Source Type: research

Treatment and Management of Spasticity.
Abstract Treatment and Management of Spasticity Abstract. In the care of neurological patients with a lesion of the first motor neuron, for example after stroke or multiple sclerosis, spasticity is a common problem with considerable impairment of quality of life. The treatment is based in the first place on therapeutic and nursing interventions. In addition, a systemic antispastic medication or, depending on the distribution of the spasticity, local injections with botulinum neurotoxin can be applied. If this is insufficient, surgical procedures may be considered. PMID: 32752967 [PubMed - indexed for MEDLINE]
Source: Praxis - July 31, 2020 Category: General Medicine Authors: Disko A Tags: Praxis (Bern 1994) Source Type: research

Concurrent maxillary herpes zoster, meningitis, focal cerebral arteriopathy, and ischemic stroke: A case report
Secondary headache, fever, and upper motor neuron signs following facial herpes zoster during childhood should alert clinicians to the possibility of central nervous system complications of varicella ‐zoster virus infection. AbstractSecondary headache, fever, and upper motor neuron signs following facial herpes zoster during childhood should alert clinicians to the possibility of central nervous system complications of varicella ‐zoster virus infection.
Source: Clinical Case Reports - August 31, 2020 Category: General Medicine Authors: Mao Liu, Jing Zhang, Mimi Wen, Min Zhang Tags: CASE REPORT Source Type: research