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Specialty: Cardiovascular & Thoracic Surgery
Condition: Heart Valve Disease

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Total 117 results found since Jan 2013.

Thirty-day VARC-2 and performance data of a new self-expanding transcatheter aortic heart valve.
CONCLUSIONS: In this first-in-human study, the feasibility of implantation of the BIOVALVE system and its re-sheathing functionality was demonstrated, and short-term safety data were encouraging. Larger studies are required to confirm the performance of the device. PMID: 25983028 [PubMed - as supplied by publisher]
Source: EuroIntervention - May 21, 2015 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

Single-centre experience with next-generation devices for transapical aortic valve implantation ADULT CARDIAC
CONCLUSIONS In a real-world clinical setting, next-generation transapical THV yielded positive haemodynamic results. The incidence of relevant paravalvular regurgitation was scarce in this group and clinical outcomes were encouraging during short-term follow-up. Long-term follow-up is required to investigate the durability of these new devices.
Source: European Journal of Cardio-Thoracic Surgery - December 11, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Seiffert, M., Conradi, L., Kloth, B., Koschyk, D., Schirmer, J., Schnabel, R. B., Blankenberg, S., Reichenspurner, H., Diemert, P., Treede, H. Tags: Electrophysiology - arrhythmias, Transplantation - heart, Basic research vascular ADULT CARDIAC Source Type: research

Aortic Valve Replacement for Severe Aortic Valve Stenosis in the Nonagenarian Patient.
CONCLUSIONS: Aortic valve replacement for severe aortic valve stenosis can be done with less than predicted operative risk in nonagenarian patients. However, transfemoral SAPIEN transcatheter heart valve transcatheter AVR should be undertaken with caution because of increased risk of vascular injury. Aortic valve replacement should not be denied in select patients. PMID: 25200726 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - September 5, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Murashita T, Greason KL, Suri RM, Nkomo VT, Holmes DR, Rihal CS, Mathew V Tags: Ann Thorac Surg Source Type: research

Predictors of stroke in patients undergoing cardiac surgery
Conclusion: The study identified the following risk predictors for stroke after cardiac surgery: age, urgent and emergency surgery, aortic valve disease, history of atrial fibrillation, peripheral artery disease, history of cerebrovascular disease and cardiopulmonary bypass time > 110 minutes. OBJETIVOS: Determinar os preditores de risco relacionados ao desenvolvimento de acidente vascular cerebral em pacientes que realizaram cirurgia cardíaca. Métodos: Estudo de coorte histórico. Incluímos 4626 pacientes com idade > 18 anos submetidos à cirurgia de revascularização do miocárdio, cirurgia cardíaca valvar is...
Source: Revista Brasileira de Cirurgia Cardiovascular - August 20, 2014 Category: Cardiovascular & Thoracic Surgery Source Type: research

The effects of a low international normalized ratio on thromboembolic and bleeding complications in patients with mechanical mitral valve replacement
Conclusions: This study showed that a target INRs of 2.0-2.5 are acceptable for preventing TEs and safe in terms of bleeding complications in patients with mechanical MVR.
Source: Journal of Cardiothoracic Surgery - May 7, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Ugur BalAlp AydinalpKerem YilmazEmre OzcalikSenem HasirciIlyas AtarBahadir GultekinAtilla SezginHaldun Muderrisoglu Source Type: research

Percutaneous heart valves; past, present and future.
Abstract Percutaneous heart valves provide a promising future for patients refused surgery on the grounds of significant technical challenges or high risk for complications. Since the first human intervention more than 10 years ago, over 50 different types of valves have been developed. The CoreValve and Edwards SAPIEN valves have both experienced clinical trials and the latter has gained FDA approval for implantation in patients considered inoperable. Current complications, such as major vascular bleeding and stroke, prevent these valves from being commonly deployed in patients considered operable in conventional...
Source: Perfusion - March 17, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Rozeik M, Wheatley D, Gourlay T Tags: Perfusion Source Type: research

Thromboembolism in a patient with a mechanical mitral valve during anticoagulation with dabigatran etexilate.
We report a 57-year-old man with a mechanical heart valve who experienced acute upper limb thromboembolism during dabigatran intake. Dabigatran might be inadequate for thromboprophylaxis after mechanical valve replacement. PMID: 24182477 [PubMed - in process]
Source: The Annals of Thoracic Surgery - November 1, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Kuwauchi S, Watanabe S, Abe K, Yamasaki M, Ito J, Kawazoe K Tags: Ann Thorac Surg Source Type: research

Early clinical outcome of aortic transcatheter valve-in-valve implantation in the Nordic countries
Conclusions: Transcatheter valve-in-valve implantation is widely performed, albeit in small numbers, in most centers in the Nordic countries. The short-term results were excellent in this high-risk patient population, demonstrating a low incidence of device- or procedure-related complications. However, a considerable number of patients were left with suboptimal systolic valve performance with unknown long-term effects, warranting close surveillance after transcatheter valve-in-valve implantation.
Source: The Journal of Thoracic and Cardiovascular Surgery - September 3, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Leo Ihlberg, Henrik Nissen, Niels-Erik Nielsen, Andreas Rück, Rolf Busund, Kaj-Erik Klaarborg, Lars Soendergaard, Jan Harnek, Heikki Miettinen, Markku Eskola, Alexander Wahba, Mika Laine Tags: Acquired Cardiovascular Disease Source Type: research

Complications after transfemoral transcatheter aortic valve replacement with a balloon‐expandable prosthesis: The importance of preventative measures and contingency planning
Abstract Transcatheter aortic valve replacement (TAVR) with balloon‐expandable Edwards‐SAPIEN valve was superior to standard therapy in inoperable patients and non‐inferior to surgical aortic valve replacement in high surgical‐risk, but operable patients, with severe symptomatic aortic stenosis in the randomized controlled PARTNER trial. Since the first case of TAVR with a balloon‐expandable valve in 2002, several groups have reported their experience with balloon‐expandable valves with high‐procedural success. In the United States, the balloon‐expandable Edwards‐SAPIEN valve is the only transcatheter hea...
Source: Catheterization and Cardiovascular Interventions - February 21, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Tarun Chakravarty, Hasan Jilaihawi, Niraj Doctor, Gregory Fontana, James S. Forrester, Wen Cheng, Raj Makkar Tags: Clinical Decision Making Source Type: research

Complications after transfemoral transcatheter aortic valve replacement with a balloon ‐expandable prosthesis: The importance of preventative measures and contingency planning
Abstract Transcatheter aortic valve replacement (TAVR) with balloon‐expandable Edwards‐SAPIEN valve was superior to standard therapy in inoperable patients and non‐inferior to surgical aortic valve replacement in high surgical‐risk, but operable patients, with severe symptomatic aortic stenosis in the randomized controlled PARTNER trial. Since the first case of TAVR with a balloon‐expandable valve in 2002, several groups have reported their experience with balloon‐expandable valves with high‐procedural success. In the United States, the balloon‐expandable Edwards‐SAPIEN valve is the only transcatheter hea...
Source: Catheterization and Cardiovascular Interventions - February 20, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Tarun Chakravarty, Hasan Jilaihawi, Niraj Doctor, Gregory Fontana, James S. Forrester, Wen Cheng, Raj Makkar Tags: Clinical Decision Making Source Type: research

Worldwide experience with the 29-mm Edwards SAPIEN XTTM transcatheter heart valve in patients with large aortic annulus ADULT CARDIAC
CONCLUSIONS The 29-mm Edwards SAPIEN XT™ bioprosthesis provides an excellent outcome in patients with a large aortic annulus undergoing transapical aortic valve implantation. Using this larger transcatheter heart valve, a broader population of high-risk elderly patients with aortic stenosis can be treated by minimally invasive transapical implantation techniques.
Source: European Journal of Cardio-Thoracic Surgery - January 13, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Wendler, O., Thielmann, M., Schroefel, H., Rastan, A., Treede, H., Wahlers, T., Eichinger, W., Walther, T. Tags: ADULT CARDIAC Source Type: research

Isolated Aortic Valve Replacement in Patients with Small Aortic Annulus-A High-Risk Group on Long-Term Follow-Up.
Conclusion Patients with small aortic annulus are predominantly small, obese, and old-aged females with multiple comorbidities. Mitroflow valve avoids prosthesis-patient mismatch and provides excellent hemodynamics. Observed long-term results were disappointing, but they were mainly limited by extracardiac comorbidities and advanced age. PMID: 23258763 [PubMed - as supplied by publisher]
Source: The Thoracic and Cardiovascular Surgeon - December 20, 2012 Category: Cardiovascular & Thoracic Surgery Authors: Wilbring M, Alexiou K, Schumann E, Matschke K, Tugtekin SM Tags: Thorac Cardiovasc Surg Source Type: research