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Peripheral Vascular Disease and Carotid Artery Disease Are Associated with Decreased Bile Acid Excretion
This study investigated BAE in patients with peripheral vascular disease (PVD) and carotid artery disease (CA) and those without these diseases, compared to patients with CAD, stroke, or no evidence of atherosclerosis. Patients with complaints of chest pain-suspected CAD, syncope, stroke/TIA, severe headache, intermittent claudication, or falls were enrolled. All received a 4-day standard diet with 490 mg of cholesterol and internal standard copper thiocyanate. Fecal BAE was measured using gas-liquid chromatography. One hundred and three patients, sixty-eight (66%) men and thirty-five women (34%), mean age range 60.9 ± 8....
Source: Atherosclerosis - August 26, 2023 Category: Cardiology Authors: Lior Charach Gideon Charach Eli Karniel Leonid Galin Dorin Bar Ziv Lior Grossman Irit Kaye Itamar Grosskopf Source Type: research

Transcranial Magnetic Stimulation as Treatment in Multiple Neurologic Conditions
AbstractPurpose of ReviewTranscranial magnetic stimulation (TMS) is a method of Non-Invasive Brain Stimulation that is based on electro-physical principles discovered by Michael Faraday. A TMS device is made of one or two copper coils, positioned superficially to a site of interest in the brain, to non-invasively produce a brief magnetic pulse to an estimated depth from the surface of the scalp with the following axonal depolarization. This axonal depolarization activates cortical and subcortical networks with multiple effects. There are different methods of TMS used, all with different mechanisms of action. TMS is well to...
Source: Current Neurology and Neuroscience Reports - February 3, 2020 Category: Neuroscience Source Type: research

Evidence-Based Contraception: Common Questions and Answers
Am Fam Physician. 2022 Sep;106(3):251-259.ABSTRACTPrimary care clinicians are uniquely situated to reduce unintended pregnancy in the context of a patient's medical comorbidities, social circumstance, and gender identity. New evidence regarding contraception use has emerged in recent years. The copper intrauterine device is the most effective option for emergency contraception, with similar effectiveness found for the levonorgestrel-releasing intrauterine system, 52 mg, and both offer extended future contraception. Ulipristal given within 120 hours after unprotected intercourse is the most effective oral emergency contrace...
Source: American Family Physician - September 20, 2022 Category: Primary Care Authors: Scott L Paradise Corinne A Landis David A Klein Source Type: research

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