Transcranial Magnetic Stimulation as Treatment in Multiple Neurologic Conditions
AbstractPurpose of ReviewTranscranial magnetic stimulation (TMS) is a method of Non-Invasive Brain Stimulation that is based on electro-physical principles discovered by Michael Faraday. A TMS device is made of one or two copper coils, positioned superficially to a site of interest in the brain, to non-invasively produce a brief magnetic pulse to an estimated depth from the surface of the scalp with the following axonal depolarization. This axonal depolarization activates cortical and subcortical networks with multiple effects. There are different methods of TMS used, all with different mechanisms of action. TMS is well tolerated with very few side effects.Recent FindingsTMS is now approved for major depression disorder and obsessive-compulsive disorder. There is significant data to consider approval of TMS for many neurological disorders. This is a review of the uses of TMS in diverse neurological conditions, including stroke and spasticity, migraine, and dementia.SummaryTMS is a device that utilizes non-invasive brain stimulation, and it has shown promising results with objective clinical and basic science data. Its ability to trigger neuronal plasticity and potentiating synaptic transmission gives it incredible therapeutic potential. There are diverse mechanisms of action, and this could be troublesome in elaborating clinical trials and standardization of therapy.
Authors: Sabet Sarvestani F, Azarpira N Abstract Heart and cerebral infarctions, as two important ischemic diseases, lead to the death of tissues due to inadequate blood supply and high mortality worldwide. These statuses are started via blockage of vessels and depletion of oxygen and nutrients which affected these areas. After reperfusion and restoration of oxygen supply, more severe injury was mediated by multifaceted cascades of inflammation and oxidative stress. microRNAs (miRNAs) as the regulator of biological and pathological pathways can adjust these conditions by interaction with their targets. Also, miRNAs...
Cupressus macrocarpa leaves for biomonitoring the environmental impact of an industrial complex: The case of Puchuncaví-Ventanas in Chile. Chemosphere. 2020 Dec;260:127521 Authors: Gorena T, Fadic X, Cereceda-Balic F Abstract The Punchuncaví Valley is one of the most polluted areas in central Chile affected by anthropogenic emissions from the Ventanas Industrial Complex (IC) where the most important industry is the copper smelter and refinery. In this context, this research aims were to assess the usefulness of the Cupressus macrocarpa as a biomonitor. The leaf samples were taken from fi...
Abstract Competitive and non-competitive batch experiments were conducted on flax fibers to study Zn2+, Cu2+, and Pb2+ ions biosorption performance. Biosorption efficiency was dependent on contact time, pH, and biosorbent concentration. The results under competitive conditions were different from those obtained in non-competitive form. A high affinity of lead, with a selectivity sequence in general of Pb > Cu > Zn was observed. The biosorption data fitted very well the Langmuir model for lead in both types of solutions and for zinc and copper in the monometal form. The fit with the Freund...
DEMENTIA can be tricky to pick up on in the earliest stages. However, mounting research indicates a certain time of day when symptoms may be more noticeable. What time do you need to be on full alert?
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