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Specialty: Cardiology
Condition: Coronary Heart Disease
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Total 1653 results found since Jan 2013.
Prevalence of hs-CRP among Indians with hypertension
Bioinformation. 2022 Oct 31;18(10):1041-1043. doi: 10.6026/973206300181041. eCollection 2022.ABSTRACTThe prevalence of hypertension in the early twentieth century varied in India, ranging from 2-15% in Urban India and 2-8% in Rural India. In the inter heart and inter stroke study, hypertension accounted for 17.9% and 34.6% of population attributable risk for coronary artery disease and stroke respectively. CRP appears in serum in response to a variety of inflammatory stimuli .Raised level of hs-CRP is seen with increasing with age, during an infection, inflammation, coronary artery diseases, obesity, sepsis, smoking and va...
Source: Atherosclerosis - September 1, 2023 Category: Cardiology Authors: Vasanthii R Kaarthikeyan G Sasirekha G Mahalakshmi S Source Type: research
Evaluation of Large-Scale Proteomics for Prediction of Cardiovascular Events
CONCLUSIONS AND RELEVANCE: A protein risk score was significantly associated with ASCVD events in primary and secondary event populations. When added to clinical risk factors, the protein risk score and polygenic risk score both provided statistically significant but modest improvement in discrimination.PMID:37606673 | DOI:10.1001/jama.2023.13258
Source: Atherosclerosis - August 22, 2023 Category: Cardiology Authors: Hannes Helgason Thjodbjorg Eiriksdottir Magnus O Ulfarsson Abhishek Choudhary Sigrun H Lund Erna V Ivarsdottir Grimur Hjorleifsson Eldjarn Gudmundur Einarsson Egil Ferkingstad Kristjan H S Moore Narimon Honarpour Thomas Liu Huei Wang Thomas Hucko Marc S S Source Type: research
What is the diameter of a fibrin fiber?
CONCLUSION: We performed a systematic, multitechnique survey assessing fibrin fiber diameters under a range of biochemical conditions. The similarity in the diameter values obtained using SEM and superresolution imaging suggests that drying and fixation during SEM sample preparation do not dramatically alter fiber cross-sections. Congruence, under certain conditions, between diameter values obtained using SEM, superresolution fluorescence imaging, and turbidimetry demonstrates the feasibility of a fibrin diameter standardization project.PMID:37601015 | PMC:PMC10439396 | DOI:10.1016/j.rpth.2023.100285
Source: Atherosclerosis - August 21, 2023 Category: Cardiology Authors: Heather A Belcher Martin Guthold Nathan E Hudson Source Type: research
Phytochemical, anti-hyperlipidemic and in silico studies of extracts of Ficus carica seeds
Pak J Pharm Sci. 2023 May;36(3(Special)):989-1000.ABSTRACTHyperlipidemia has been considered a disease primarily causing death along with other prevailing diseases such as coronary heart diseases, atherosclerosis and stroke. The present study aims to evaluate the anti-hyperlipidemic potential of Ficus carica. Extracts of seeds of Ficus carica were investigated for bioactive compounds and screened using in-vitro and in-vivo anti-hyperlipidemic activities. Fig seeds showed potential in-vitro by inhibition of pancreatic lipase while in-vivo study revealed that methanol extract of fig seeds exhibited the anti-hyperlipidemic pr...
Source: Atherosclerosis - August 17, 2023 Category: Cardiology Authors: Saira Fayyaz Muhammad Islam Abrar Ahmed Hamid Saeed Ayesha Naseem Source Type: research
Plasma Trimethylamine- < em > N < /em > -Oxide and Incident Ischemic Stroke: The Cardiovascular Health Study and the Multi-Ethnic Study of Atherosclerosis
Conclusions Plasma TMAO levels are associated with incident ischemic stroke in a diverse population. Registration URL: https://www.clinicaltrials.gov. Unique identifier: NCT00005133.PMID:37581385 | DOI:10.1161/JAHA.122.029230
Source: Atherosclerosis - August 15, 2023 Category: Cardiology Authors: Rozenn N Lemaitre Paul N Jensen Zeneng Wang Amanda M Fretts Colleen M Sitlani Ina Nemet Nona Sotoodehnia Marcia C de Oliveira Otto Weifei Zhu Matt Budoff W T Longstreth Bruce M Psaty David S Siscovick Stanley L Hazen Dariush Mozaffarian Source Type: research
Age-Related Differences in the Contribution of Systolic Blood Pressure and Biomarkers to Cardiovascular Disease Risk Prediction: The Atherosclerosis Risk in Communities (ARIC) Study
Am J Cardiol. 2023 Aug 9;204:295-301. doi: 10.1016/j.amjcard.2023.07.118. Online ahead of print.ABSTRACTWe sought to determine how biomarkers known to be associated with hypertension-induced end-organ injury complement the use of systolic blood pressure (SBP) for cardiovascular disease (CVD) risk prediction at different ages. Using data from visits 2 (1990 to 1992) and 5 (2011 to 2013) of the Atherosclerosis Risk in Communities (ARIC) study, 3 models were used to predict CVD (composite of coronary heart disease, stroke, and heart failure). Model A included traditional risk factors (TRFs) except SBP, model B-TRF plus SBP, a...
Source: Atherosclerosis - August 11, 2023 Category: Cardiology Authors: Mahmoud Al Rifai George E Taffet Kunihiro Matsushita Salim S Virani James De Lemos Amit Khera Jarrett Berry Chiadi Ndumele David Aguilar Caroline Sun Ron C Hoogeveen Elizabeth Selvin Christie M Ballantyne Vijay Nambi Source Type: research
Genes That Extend Lifespan May Do So by Mitigating the Increased Risk of Death Posed by Having Hypertension
Am J Hypertens. 2023 Aug 10:hpad070. doi: 10.1093/ajh/hpad070. Online ahead of print.ABSTRACTGenetic factors influence lifespan. In humans, there appears to be a particularly strong genetic effect in those aged ≥ 90 years. An important contribution is nutrient sensing genes which confer cell resilience. Our research has been investigating the genetic factors by longitudinal studies of American men of Japanese descent living on the island of Oahu in Hawaii. This cohort began as the Honolulu Heart Program in the mid-1960s and most subjects are now deceased. We previously discovered various genes containing polymorphisms as...
Source: American Journal of Hypertension - August 10, 2023 Category: Cardiology Authors: Brian J Morris Timothy A Donlon Source Type: research
Bioinformatic platforms for clinical stratification of natural history of atherosclerotic cardiovascular diseases
Eur Heart J Cardiovasc Pharmacother. 2023 Aug 10:pvad059. doi: 10.1093/ehjcvp/pvad059. Online ahead of print.ABSTRACTAlthough bioinformatic methods gained a lot of attention in the latest years, their use in real-world studies for primary and secondary prevention of atherosclerotic cardiovascular diseases (ASCVD) is still lacking. Bioinformatic resources have been applied to thousands of individuals from the Framingham Heart Study as well as health care-associated biobanks such as the UK Biobank, the Million Veteran Program, and the CARDIoGRAMplusC4D Consortium and randomized controlled trials (i.e. ODYSSEY, FOURIER, ASPRE...
Source: Atherosclerosis - August 10, 2023 Category: Cardiology Authors: Giuditta Benincasa Rosa Suades Teresa Padr ò Lina Badimon Claudio Napoli Source Type: research
Age-Related Differences in the Contribution of Systolic Blood Pressure and Biomarkers to Cardiovascular Disease Risk Prediction: The Atherosclerosis Risk in Communities (ARIC) Study
We sought to determine how biomarkers known to be associated with hypertension-induced end-organ injury complement the use of systolic blood pressure (SBP) for cardiovascular disease (CVD) risk prediction at different ages. Using data from visits 2 (1990 to 1992) and 5 (2011 to 2013) of the Atherosclerosis Risk in Communities (ARIC) study, 3 models were used to predict CVD (composite of coronary heart disease, stroke, and heart failure). Model A included traditional risk factors (TRFs) except SBP, model B —TRF plus SBP, and model C—TRF plus biomarkers (high-sensitivity troponin T [hsTnT] and N-terminal pro-B-type natri...
Source: The American Journal of Cardiology - August 9, 2023 Category: Cardiology Authors: Mahmoud Al Rifai, George E. Taffet, Kunihiro Matsushita, Salim S. Virani, James De Lemos, Amit Khera, Jarrett Berry, Chiadi Ndumele, David Aguilar, Caroline Sun, Ron C. Hoogeveen, Elizabeth Selvin, Christie M. Ballantyne, Vijay Nambi Source Type: research
Coronary artery disease grading by cardiac CT for predicting outcome in patients with stable angina
CONCLUSION: In patients referred for invasive angiography, a history of CHD was the strongest predictor of MACE. In patients without history of CHD, a coronary calcium score yielded at least equal risk stratification vs. more complex CHD grading.PMID:37541910 | DOI:10.1016/j.jcct.2023.07.004
Source: Atherosclerosis - August 4, 2023 Category: Cardiology Authors: Christian U Oeing Matthew B Matheson Mohammad R Ostovaneh Carlos E Rochitte Marcus Y Chen Burkert Pieske Klaus F Kofoed Joanne D Schuijf Hiroyuki Niinuma Marc Dewey Marcelo F di Carli Christopher Cox Jo ão A C Lima Armin Arbab-Zadeh Source Type: research
Is Improving Educational Attainment Key to Reducing the Burden Because of Cardiovascular Diseases?
Cardiovascular diseases (CVDs) impose a substantial global public health burden, accounting for significant mortality and disability worldwide, particularly because of conditions like coronary heart disease and stroke. The economic consequences of CVDs, including healthcare expenses, decreased productivity, and diminished quality of life, further contribute to this burden. Lifestyle factors such as unhealthy diets, physical inactivity, tobacco use, and excessive alcohol consumption are closely associated with CVDs.
Source: The American Journal of Cardiology - August 1, 2023 Category: Cardiology Authors: Jari Antero Laukkanen, Setor Kwadzo Kunutsor Tags: Editorial Source Type: research
The role of atherogenic dyslipidemia, endothelial dysfunction and systemic inflammation in the development of vascular complications in patients with NAFLD
Background and Aims: Patients with NAFLD are at high risk of coronary heart disease and stroke, but the mechanisms are not yet fully understood. Aim is to determine the relationship between atherogenic dyslipidemia, systemic inflammation, endothelial dysfunction as causes of cardiovascular complications in patients with NAFLD.
Source: Atherosclerosis - August 1, 2023 Category: Cardiology Authors: K. Pivtorak, I. Fedzhaga, O. Marchuk, N. Pivtorak Source Type: research
