Filtered By:
Condition: Dementia
Education: Conferences

This page shows you your search results in order of date.

Order by Relevance | Date

Total 42 results found since Jan 2013.

Study protocol for development and validation of a single tool to assess risks of stroke, diabetes mellitus, myocardial infarction and dementia: DemNCD-Risk
Introduction Current efforts to reduce dementia focus on prevention and risk reduction by targeting modifiable risk factors. As dementia and cardiometabolic non-communicable diseases (NCDs) share risk factors, a single risk-estimating tool for dementia and multiple NCDs could be cost-effective and facilitate concurrent assessments as compared with a conventional single approach. The aim of this study is to develop and validate a new risk tool that estimates an individual’s risk of developing dementia and other NCDs including diabetes mellitus, stroke and myocardial infarction. Once validated, it could be used by the ...
Source: BMJ Open - September 22, 2023 Category: General Medicine Authors: Kootar, S., Huque, M. H., Kiely, K. M., Anderson, C. S., Jorm, L., Kivipelto, M., Lautenschlager, N. T., Matthews, F., Shaw, J. E., Whitmer, R. A., Peters, R., Anstey, K. J. Tags: Open access, Public health Source Type: research

Multicohort cross-sectional study of cognitive and behavioural digital biomarkers in neurodegeneration: the Living Lab Study protocol
Introduction and aims Digital biomarkers can provide a cost-effective, objective and robust measure for neurological disease progression, changes in care needs and the effect of interventions. Motor function, physiology and behaviour can provide informative measures of neurological conditions and neurodegenerative decline. New digital technologies present an opportunity to provide remote, high-frequency monitoring of patients from within their homes. The purpose of the living lab study is to develop novel digital biomarkers of functional impairment in those living with neurodegenerative disease (NDD) and neurological condi...
Source: BMJ Open - August 3, 2023 Category: General Medicine Authors: Crook-Rumsey, M., Daniels, S. J. C., Abulikemu, S., Lai, H., Rapeaux, A., Hadjipanayi, C., Soreq, E., Li, L. M., Bashford, J., Jeyasingh-Jacob, J., Gruia, D. C., Lambert, D., Weil, R., Hampshire, A., Sharp, D. J., Haar, S. Tags: Open access, Neurology Source Type: research

Statins for extension of disability-free survival and primary prevention of cardiovascular events among older people: protocol for a randomised controlled trial in primary care (STAREE trial)
Introduction The world is undergoing a demographic transition to an older population. Preventive healthcare has reduced the burden of chronic illness at younger ages but there is limited evidence that these advances can improve health at older ages. Statins are one class of drug with the potential to prevent or delay the onset of several causes of incapacity in older age, particularly major cardiovascular disease (CVD). This paper presents the protocol for the STAtins in Reducing Events in the Elderly (STAREE) trial, a randomised double-blind placebo-controlled trial examining the effects of statins in community dwelling o...
Source: BMJ Open - April 3, 2023 Category: General Medicine Authors: Zoungas, S., Curtis, A., Spark, S., Wolfe, R., McNeil, J. J., Beilin, L., Chong, T. T.-J., Cloud, G., Hopper, I., Kost, A., Nelson, M., Nicholls, S. J., Reid, C. M., Ryan, J., Tonkin, A., Ward, S. A., Wierzbicki, A., On behalf of STAREE investigator group Tags: Open access, Cardiovascular medicine Source Type: research

ADVANCE-TBI study protocol: traumatic brain injury outcomes in UK military personnel serving in Afghanistan between 2003 and 2014 - a longitudinal cohort study
Introduction Outcomes of traumatic brain injury (TBI) are highly variable, with cognitive and psychiatric problems often present in survivors, including an increased dementia risk in the long term. Military personnel are at an increased occupational risk of TBI, with high rates of complex polytrauma including TBI characterising the UK campaign in Afghanistan. The ArmeD SerVices TrAuma and RehabilitatioN OutComE (ADVANCE)-TBI substudy will describe the patterns, associations and long-term outcomes of TBI in the established ADVANCE cohort. Methods and analysis The ADVANCE cohort comprises 579 military personnel exposed to m...
Source: BMJ Open - March 21, 2023 Category: General Medicine Authors: Graham, N. S. N., Blissitt, G., Zimmerman, K., Friedland, D., Dumas, M.-E., Coady, E., Heslegrave, A., Zetterberg, H., Escott-Price, V., Schofield, S., Fear, N. T., Boos, C., Bull, A. M. J., Cullinan, P., Bennett, A., Sharp, D. J., for the ADVANCE Study Tags: Open access, Neurology Source Type: research

As some hail new antibody treatment for Alzheimer ’s, safety and benefit questions persist
In a packed San Francisco conference room with a celebratory atmosphere, upbeat company representatives and scientists yesterday presented detailed clinical trial data on the first Alzheimer’s treatment shown to clearly, albeit modestly, slow the disease’s normal cognitive decline. The antibody therapy has buoyed a field marked by decades of failures. Now, it appears to be on the cusp of being greenlit by the U.S. Food and Drug Administration (FDA). Yet other researchers warn of potential risks, including brain swelling and brain hemorrhages that were linked to the recently disclosed deaths of two trial participants wh...
Source: Science of Aging Knowledge Environment - December 1, 2022 Category: Geriatrics Source Type: research

A Scoping Review of the Incidence, Predictors, and Outcomes of Delirium Among Critically Ill Stroke Patients
CONCLUSIONS: Current findings are limited by heterogenous populations, assessments, and measurement parameters. Detection and management of delirium among critically ill stroke patients requires an approach with specific considerations to the complexities of acute neurological injury and concomitant critical illness.
Source: Journal of Neuroscience Nursing - May 13, 2022 Category: Neuroscience Tags: Articles Source Type: research

Do P2Y12 receptor inhibitors prescribed poststroke modify the risk of cognitive disorder or dementia? Protocol for a target trial using multiple national Swedish registries
This study has been approved by the Ethics Committee of the University of Gothenburg and Confidentiality Clearance at Statistics Sweden with Dnr 937-18, and an approved addendum with Dnr 2019-0157. The analysis and interpretation of the results will be heavily reliant on the structure, quality and potential for bias of the databases used. When we implement the protocol, we will consider and document any biases specific to the dataset and conduct appropriate sensitivity analyses. Findings will be disseminated to local stakeholders via conferences, and published in appropriate scientific journals.
Source: BMJ Open - May 9, 2022 Category: General Medicine Authors: Hinwood, M., Nyberg, J., Leigh, L., Gustavsson, S., Attia, J., Oldmeadow, C., Ilicic, M., Linden, T., Aberg, N. D., Levi, C., Spratt, N., Carey, L. M., Pollack, M., Johnson, S. J., Kuhn, G. H., Walker, F. R., Nilsson, M. Tags: Open access, Neurology Source Type: research

Assessment of time-related deficits in older adults: a scoping review protocol
Introduction People with cognitive impairments often have difficulties in managing their time for daily activities. In older adults with cognitive impairments such as dementia and stroke, these may present as disorientation, poor time awareness, time perception, daily time management and so on. Time-related deficits and associated behaviours impede independent living and add considerably to caregiver strain. Several interventions are being investigated to help people with cognitive impairments orient and navigate time and do their daily activities. The provision of interventions requires the use of sound assessment tools. ...
Source: BMJ Open - September 24, 2021 Category: General Medicine Authors: Dsouza, S. A., Ramachandran, M., Nishiura, Y., Venkatesh, B. T., Dahlberg, L. Tags: Open access, Occupational and environmental medicine Source Type: research

Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the detection of dementia within community dwelling populations
CONCLUSIONS: Published data suggest that if using the IQCODE for community dwelling older adults, the 16 item IQCODE may be preferable to the traditional scale due to lesser test burden and no obvious difference in accuracy. Although IQCODE test accuracy is in a range that many would consider 'reasonable', in the context of community or population settings the use of the IQCODE alone would result in substantial misdiagnosis and false reassurance. Across the included studies there were issues with heterogeneity, several potential biases and suboptimal reporting quality.PMID:34278562 | DOI:10.1002/14651858.CD010079.pub3
Source: Cochrane Database of Systematic Reviews - July 19, 2021 Category: General Medicine Authors: Terry J Quinn Patricia Fearon Anna H Noel-Storr Camilla Young Rupert McShane David J Stott Source Type: research

Informant Questionnaire on Cognitive Decline in the Elderly (IQCODE) for the early detection of dementia across a variety of healthcare settings
CONCLUSIONS: Included studies were heterogenous, recruited from specialist settings, and had potential biases. The studies identified did not allow us to make specific recommendations on the use of the IQCODE for the future detection of dementia in clinical practice. The included studies highlighted the challenges of delayed verification dementia research, with issues around prevalent dementia assessment, loss to follow-up over time, and test non-completion potentially limiting the studies. Future research should recognise these issues and have explicit protocols for dealing with them.PMID:34275145 | DOI:10.1002/14651858.CD011333.pub3
Source: Cochrane Database of Systematic Reviews - July 18, 2021 Category: General Medicine Authors: Jennifer K Burton David J Stott Rupert McShane Anna H Noel-Storr Rhiannon S Swann-Price Terry J Quinn Source Type: research

ASA: Retinopathy Linked to Increased Risk for Stroke, Dementia
THURSDAY, March 11, 2021 -- Retinopathy is associated with an increased risk for stroke and dementia, according to a study presented at the American Stroke Association International Stroke Conference, held virtually from March 17 to 19. Michelle P....
Source: Drugs.com - Pharma News - March 11, 2021 Category: Pharmaceuticals Source Type: news

Food as Prevention – Rising to Nutritional Challenges
Mothers and their children gather at a community nutrition centre in the little village of Rantolava, Madagascar, to learn more about a healthy diet. Credit: Alain Rakotondravony/IPSBy Gabriele RiccardiNAPLES, Italy, Nov 25 2020 (IPS) The risks factors contributing to the dramatic rise in non-communicable diseases (NCDs) in recent decades have been known for a long time but the Covid-19 pandemic has brutally exposed our collective failure to deal with them. Reporting on the findings of the latest Global Burden of Disease Study, The Lancet warns of a “perfect storm” created by the interaction of the highly infectious C...
Source: IPS Inter Press Service - Health - November 25, 2020 Category: International Medicine & Public Health Authors: Gabriele Riccardi Tags: Development & Aid Economy & Trade Featured Food Security and Nutrition Food Sustainability Global Headlines Health Humanitarian Emergencies Inequity Poverty & SDGs TerraViva United Nations Barilla Center for Food and Nutrition Foun Source Type: news

Neurological Involvement in Primary Systemic Vasculitis
Conclusion Neurological involvement is a common complication of PSV (Table 1), and neurologists play an important role in the identification and diagnosis of PSV patients with otherwise unexplained neurological symptoms as their chief complaint. This article summarizes the neurological manifestations of PSV and hopes to improve neuroscientists' understanding of this broad range of diseases. TABLE 1 Table 1. Common CNS and PNS involvements of primary systemic vasculitis. Author Contributions SZ conceived the article and wrote the manuscript. DY and GT reviewed and edited the manuscript. All authors ...
Source: Frontiers in Neurology - April 25, 2019 Category: Neurology Source Type: research

The Predictive Capacity of the Buffalo Concussion Treadmill Test After Sport-Related Concussion in Adolescents
Conclusion This study found that the ΔHR (HRt minus resting HR) correlated with duration of clinical recovery in participants who were prescribed relative rest or a placebo-stretching program but not for participants prescribed sub-threshold aerobic exercise. A ΔHR of ≤50 bpm on the BCTT was 73% sensitive and 78% specific for predicting delayed recovery in concussed adolescents prescribed the current standard of care (i.e., cognitive and physical rest). This has implications for planning team and school activities in adolescents who sustain SRC. Ethics Statement This study was carried out in acco...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research