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Condition: Bleeding
Therapy: Dialysis

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Total 447 results found since Jan 2013.

Perioperative outcomes after on- and off-pump coronary artery bypass grafting.
Abstract Although numerous reports describe the results of off-pump coronary artery bypass grafting (CABG) at specialized centers and in select patient populations, it remains unclear how off-pump CABG affects real-world patient outcomes. We conducted a large, multicenter observational cohort study of perioperative death and morbidity in on-pump (ON) versus off-pump (OFF) CABG. We reviewed Veterans Affairs Surgical Quality Improvement Program data for all patients (N=65,097) who underwent isolated CABG from October 1997 through April 2011 (intention-to-treat data were available from 2005 onward). The primary outco...
Source: Texas Heart Institute Journal - April 1, 2014 Category: Cardiology Authors: Bakaeen FG, Chu D, Kelly RF, Holman WL, Jessen ME, Ward HB Tags: Tex Heart Inst J Source Type: research

P113 * Clinical outcomes following double and triple valve surgery in Hong Kong
Conclusion: Patient requiring double and triple valve surgeries represent a heterogeneous and complex group of patients. They are a significant portion of patients undergoing valve surgery in our Institution. Outcomes in comparison to pre-operative risk scores and International Databases are satisfactory.
Source: European Journal of Heart Failure Supplements - February 23, 2012 Category: Cardiology Authors: Wong, H. L., Ng, S. H., Kwok, W. T., Yeung, C. L., Yu, S. Y., Wan, Y. P., Wan, S., Underwood, M. J., Bai, W. J., Li, H., Tang, H., Wang, H., Rao, L., Li, H., Bai, W. J., Chen, Y., Tang, H., Peng, Y., Rao, L., Park, Y. H., Han, D. C., Sohn, C. B., Kim, J. Tags: Valvular Heart Disease Source Type: research

210 * contemporary approach of thoraco-abdominal aortic repair using moderate to deep hypothermia combined with target reconstruction of the adamkiewicz artery
Conclusion: Moderate to deep hypothermia combined with target reconstruction of the Adamkiewicz artery brings satisfactory outcomes in thoraco-abdominal aortic repair, especially for spinal cord protection.
Source: Interactive CardioVascular and Thoracic Surgery - September 23, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Tanaka, H., Minatoya, K., Sasaki, H., Oda, T., Itonaga, T., Kobayashi, J. Tags: Thoraco-abdominal aortic repair reloaded Source Type: research

Perioperative Aspirin and Clonidine and Risk of Acute Kidney Injury
In this sub-study of the POISE-2 study, neither ASA or clonidine reduced the risk of acute kidney injury after non-cardiac surgery. Of note, aspirin increased the risk of major bleeding (which was associated with a greater risk of acute kidney injury).  As well, clonidine increased the risk of clinically important hypotension (which was associated with a greater risk of acute kidney injury). : Stroke and Bleeding in Atrial Fibrillation with Chronic Kidney Disease Risk of acute kidney injury associated with the use of fluoroquinolones Chronic Dialysis and Death Among Survivors of Acute Kidney Injury Requiring Dialysis
Source: Nephrology Now - November 16, 2014 Category: Urology & Nephrology Authors: Nephrology Now editors Tags: Acute Kidney Injury Source Type: research

Clopidogrel Use in End‐Stage Kidney Disease
In conclusion, current evidence suggests that ESKD patients may not derive the same benefits from clopidogrel therapy as the general population and this therapy may be associated with harm. Properly designed observational studies and randomized controlled trials are needed to establish the role of clopidogrel in patients with ESKD, the use of platelet assays to tailor therapy, and the role of other antiplatelet agents such as prasugrel or ticagrelor in patients who exhibit high on‐treatment residual platelet reactivity.
Source: Seminars In Dialysis - November 1, 2014 Category: Hematology Authors: Bassem Y. Tanios, Houssam S. Itani, Deborah L. Zimmerman Tags: Review Source Type: research

Clopidogrel Use in End-Stage Kidney Disease.
In conclusion, current evidence suggests that ESKD patients may not derive the same benefits from clopidogrel therapy as the general population and this therapy may be associated with harm. Properly designed observational studies and randomized controlled trials are needed to establish the role of clopidogrel in patients with ESKD, the use of platelet assays to tailor therapy, and the role of other antiplatelet agents such as prasugrel or ticagrelor in patients who exhibit high on-treatment residual platelet reactivity. PMID: 25476742 [PubMed - as supplied by publisher]
Source: Seminars in Dialysis - December 5, 2014 Category: Urology & Nephrology Authors: Tanios BY, Itani HS, Zimmerman DL Tags: Semin Dial Source Type: research

Results of “elephant trunk” total aortic arch replacement using a multi-branched, collared graft prosthesis
We report on our experience with a simplified elephant trunk (ET) procedure with a multi-branched prosthesis (Vascutek® Siena™ Collared Graft). It consists of a proximal portion (20 cm) with prefabricated side branches, a collar and a distal portion (30 cm). The collar, which can be trimmed into any desired diameter, constitutes the suture portion to the descending aorta. Radiopaque markers in the distal portion indicate the landing zone. Between January 2011 and June 2013, 20 consecutive patients (10 women; mean age, 66 ± 9.3 years) underwent ET procedure, including 6 re-do cases. Underlying aortic diseases were ...
Source: Heart and Vessels - December 9, 2014 Category: Cardiology Source Type: research

Does concomitant tricuspid annuloplasty increase perioperative mortality and morbidity when correcting left-sided valve disease?
In conclusion, there is good evidence to support that tricuspid annuloplasty is a low-risk procedure and concomitant TV repair does not significantly increase the perioperative mortality and morbidity when correcting left-sided valve disease.
Source: Interactive CardioVascular and Thoracic Surgery - December 18, 2014 Category: Cardiovascular & Thoracic Surgery Authors: Zhu, T.-Y., Wang, J.-G., Meng, X. Tags: Basic research vascular Adult Cardiac Source Type: research

Impact of postoperative acute kidney injury on clinical outcomes after TAVI: A meta‐analysis of 5,971 patients
Conclusions: Postoperative AKI seems to significantly worsen TAVI prognosis. The results of the present meta‐analysis should be considered hypothesis‐generating and future studies on risk stratification, prevention and postoperative management are needed. This article is protected by copyright. All rights reserved.
Source: Catheterization and Cardiovascular Interventions - January 30, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Giuseppe Gargiulo, Anna Sannino, Davide Capodanno, Cinzia Perrino, Piera Capranzano, Marco Barbanti, Eugenio Stabile, Bruno Trimarco, Corrado Tamburino, Giovanni Esposito Tags: Original Studie Source Type: research

Moderate and Severe Preoperative Chronic Kidney Disease Worsen Clinical Outcomes After Transcatheter Aortic Valve Implantation: Meta-Analysis of 4992 Patients Structural Heart Disease
Conclusions— Both moderate and severe preoperative CKD significantly worsen transcatheter aortic valve implantation prognosis. Future studies on risk evaluation, prevention, and postoperative management are needed.
Source: Circulation: Cardiovascular Interventions - February 4, 2015 Category: Cardiology Authors: Gargiulo, G., Capodanno, D., Sannino, A., Perrino, C., Capranzano, P., Stabile, E., Trimarco, B., Tamburino, C., Esposito, G. Tags: Catheter-based coronary and valvular interventions: other Structural Heart Disease Source Type: research

Impact of postoperative acute kidney injury on clinical outcomes after transcatheter aortic valve implantation: A meta‐analysis of 5,971 patients
ConclusionsPostoperative AKI seems to significantly worsen TAVI prognosis. The results of the present meta‐analysis should be considered hypothesis‐generating and future studies on risk stratification, prevention, and postoperative management are needed. © 2015 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - February 17, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Giuseppe Gargiulo, Anna Sannino, Davide Capodanno, Cinzia Perrino, Piera Capranzano, Marco Barbanti, Eugenio Stabile, Bruno Trimarco, Corrado Tamburino, Giovanni Esposito Tags: Valvular and Structural Heart Diseases Source Type: research

Recent thoraco-abdominal aortic repair outcomes using moderate-to-deep hypothermia combined with targeted reconstruction of the Adamkiewicz artery
CONCLUSIONS Moderate-to-deep hypothermia combined with targeted reconstruction of the AKA provided satisfactory outcomes with thoraco-abdominal aortic repair, particularly for spinal cord protection.
Source: Interactive CardioVascular and Thoracic Surgery - April 22, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Tanaka, H., Minatoya, K., Sasaki, H., Seike, Y., Itonaga, T., Oda, T., Kobayashi, J. Tags: Pericardium Adult Cardiac Source Type: research

Abstract 350: Impact of Acute Kidney Injury on Outcomes of Patients Admitted with Unstable Angina in United States, Years 2005-2011 Session Title: Poster Session III
Conclusions: In patients with UA, AKI is associated with significantly higher rates of in-hospital complications and mortality.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Awan, M. U., Malik, A., Akram, Y., Adil, M. M. Tags: Session Title: Poster Session III Source Type: research

Management of Bleeding Complications in Patients Taking Direct Oral Anticoagulants at a Large Tertiary Academic Medical Center
Abstract Direct oral anticoagulants (DOACs) offer a fixed-dose alternative to warfarin for stroke prevention in patients with atrial fibrillation. However, there is minimal evidence to guide the management of bleeding in patients taking a DOAC. We retrospectively evaluated the acute management of major bleeding in this patient population at a large, tertiary academic medical center. We evaluated various strategies of management including dialysis, transfusions, pharmacologic agents, surgical intervention, and reinitiation of anticoagulation. We also assessed length of intensive care unit and hospital stay, mor...
Source: Current Emergency and Hospital Medicine Reports - June 13, 2015 Category: Emergency Medicine Source Type: research

Challenging the use of warfarin in patients on dialysis with atrial fibrillation
Nature Reviews Nephrology 11, 450 (2015). doi:10.1038/nrneph.2015.87 Authors: Georg Schlieper & Jürgen Floege We read with great interest the article from Qamar and Bhatt (Anticoagulation therapy: Balancing the risks of stroke and bleeding in CKD. Nat. Rev. Nephrol.11, 200–202; 2015) that discussed the observational study by Bonde et al. on anticoagulation
Source: Nature Reviews Nephrology - July 7, 2015 Category: Urology & Nephrology Authors: Georg SchlieperJürgen Floege Tags: Correspondence Source Type: research