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Psychological and social health outcomes of physical activity around menopause: A scoping review of research
Menopause is generally defined as the permanent cessation of menstruation and is usually categorized into premenopausal, perimenopausal and postmenopausal stages, defined on the basis of endocrine status and regularity of menstrual bleeding pattern [1]. Physiological research has shown that endocrine changes related to menopause involve a higher risk of several forms of cardiovascular disease, such as heart attack, stroke and atherosclerosis, as well as osteoporosis [2].
Source: Maturitas - August 3, 2022 Category: Primary Care Authors: Maria Hybholt Tags: Review article Source Type: research

When hormonal treatment is not an option
An integrated analysis of safety data from seven Phase 2/3 double-blind, placebo-controlled trials has been conducted for ospemifene (Senshio ®). Adverse drug reactions are well characterized, benign and not unexpected from a SERM used for the treatment of VVA (i.e. hot flushes, leg cramps). There is no evidence to date that ospemifene leads to an increase in vaginal bleeding, endometrial hyperplasia or cancer; VTE, stroke or other cardi ovascular events; or any other adverse event of special interest.
Source: Maturitas - February 14, 2018 Category: Primary Care Authors: Felix Lugo Source Type: research