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Specialty: Drugs & Pharmacology
Condition: Bleeding

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Total 688 results found since Jan 2013.

Cardiovascular Protection of Aspirin in Chronic Kidney Disease Patients: An Updated Systematic Review and Meta-Analysis
CONCLUSION: Aspirin did not prevent CV events, with a significantly increased risk of minor bleeding and renal events. Besides, aspirin use had no statistically significant reduction in the risk of all-cause mortality but had a statistically significant reduction in the risk of CV mortality.PMID:37259222 | DOI:10.2174/1570161121666230530154647
Source: Current Vascular Pharmacology - June 1, 2023 Category: Drugs & Pharmacology Authors: Ting Chen Yunlei Deng Rong Gong Source Type: research

New pharmacotherapeutic options for oral anticoagulant treatment in atrial fibrillation patients aged 65 and older: factor XIa inhibitors and beyond
This article reviews current pharmacotherapeutic options in this setting. Particular emphasis is placed on the ability of the new molecules to minimize the bleeding risk in elderly patients. A systematic search of PubMed, Web of Science, and the Cochrane Library up to March 2023 was carried out.EXPERT OPINION: Contact phase of coagulation is a possible new target for anticoagulant therapy. Indeed, congenital or acquired deficiency of contact phase factors is associated with reduced thrombotic burden and limited risk of spontaneous bleeding. These new drugs seem particularly suitable for stroke prevention in elderly patient...
Source: Expert Opinion on Pharmacotherapy - May 27, 2023 Category: Drugs & Pharmacology Authors: Giovanni Santostasi Gentian Denas Vittorio Pengo Source Type: research

Clinical effectiveness of sodium fluorescein-guided microsurgery in patients with high-grade gliomas
CONCLUSIONS: Fluorescein-guided microsurgery can dramatically improve total resection rate, postoperative neurological functional status, and overall survival with higher efficacy and safety in patients with high-grade gliomas.PMID:37203814 | DOI:10.26355/eurrev_202305_32296
Source: Pharmacological Reviews - May 19, 2023 Category: Drugs & Pharmacology Authors: G-B Wang W-X Wang J-J Luo Source Type: research