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Source: Journal of Vascular Surgery
Condition: Bleeding
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Total 21 results found since Jan 2013.
Prevention of Stroke With Ticagrelor in Patients With Prior Myocardial Infarction: Insights from PEGASUS-TIMI 54 (Prevention of Cardiovascular Events in Patients With Prior Heart Attack Using Ticagrelor Compared to Placebo on a Background of Aspirin-Thrombolysis in Myocardial Infarction)
In patients with prior myocardial infarction, ticagrelor 60 mg twice daily reduces risk of stroke without an excess of hemorrhagic stroke but with more major bleeding.
Source: Journal of Vascular Surgery - December 20, 2016 Category: Surgery Authors: M.P. Bonaca, S. Goto, D.L. Bhatt Tags: Abstract Source Type: research
Shared quality data are associated with increased protamine use and reduced bleeding complications after carotid endarterectomy in the Vascular Study Group of New England
Objective: The goal of this study was to evaluate whether protamine usage after carotid endarterectomy (CEA) increased within the Vascular Study Group of New England (VSGNE) in response to studies indicating that protamine reduces bleeding complications associated with CEA without increasing the risk of stroke.Methods: We reviewed 10,059 CEAs, excluding concomitant coronary bypass, performed within the VSGNE from January 2003 to July 2012. Protamine use and reoperation for bleeding were evaluated monthly using statistical process control. Twelve centers and 77 surgeons entering the VSGNE between 2003 and 2008 were classifi...
Source: Journal of Vascular Surgery - September 9, 2013 Category: Surgery Authors: Reshma B. Patel, Peter Beaulieu, Karen Homa, Philip P. Goodney, Andrew C. Stanley, Jack L. Cronenwett, David H. Stone, Daniel J. Bertges, Vascular Study Group of New England Tags: Clinical research studies Source Type: research
Race as a predictor of morbidity, mortality, and neurologic events after carotid endarterectomy
Objective: Racial disparities in the outcomes of patients undergoing carotid endarterectomy (CEA) have been reported. We sought to examine the contemporary relationship between race and outcomes and to report postdischarge events after CEA.Methods: The American College of Surgeons National Surgical Quality Improvement Program Participant Use Data Files were reviewed to identify all CEAs performed from 2005 to 2010 by vascular surgeons. The influence of race on outcomes was examined. Multivariate analysis was performed using variables found to be significant on bivariate analysis. The primary outcomes were stroke and mortal...
Source: Journal of Vascular Surgery - February 1, 2013 Category: Surgery Authors: Hilary A. Brown, Michael C. Sullivan, Richard G. Gusberg, Alan Dardik, Julie Ann Sosa, Jeffrey E. Indes Tags: Clinical research studies Source Type: research
Contemporary outcomes after distal vertebral reconstruction
Conclusions: Distal VA reconstruction for flow-limiting or embolic lesions provides excellent stroke protection and symptomatic relief with acceptable perioperative risk in selected patients.
Source: Journal of Vascular Surgery - March 13, 2013 Category: Surgery Authors: Dawn M. Coleman, Andrea Obi, Enrique Criado, Shipra Arya, Ramon Berguer Tags: Clinical research studies Source Type: research
Dual antiplatelet therapy (clopidogrel and aspirin) is associated with increased all-cause mortality after carotid revascularization for asymptomatic carotid disease
Conclusions: In this retrospective, single-institution study, the use of dual antiplatelet therapy (aspirin plus clopidogrel) in patients intervened for asymptomatic carotid disease was related to increased all-cause mortality, whereas it did not significantly influence the outcome in patients with symptomatic carotid disease.
Source: Journal of Vascular Surgery - February 3, 2014 Category: Surgery Authors: Francisco Alcocer, Zdenek Novak, Bart R. Combs, Bruce Lowman, Marc A. Passman, Marjan Mujib, William D. Jordan Tags: Clinical research studies Source Type: research
Drain Placement Confers No Benefit Following Carotid Endarterectomy in the Vascular Quality Initiative
Whereas bleeding complications requiring a return to the operating room (OR) after carotid endarterectomy (CEA) are infrequent (1%), they are associated with increased 30-day combined postoperative stroke/death rate. Drain placement (DR) after CEA varies among vascular surgeons, and there are limited data to support the practice. The goal of this study was to evaluate factors leading to DR and the effect of DR on postoperative outcomes including return to OR for bleeding, stroke, and death.
Source: Journal of Vascular Surgery - August 23, 2016 Category: Surgery Authors: Christopher J. Smolock, Jeanwan Kang, James F. Bena, Nayara Cioffi Batagini, Rebecca Kelso, Daniel Clair Tags: Abstract from the 2016 Eastern Vascular Society Annual Meeting Source Type: research
Drain placement confers no benefit after carotid endarterectomy in the Vascular Quality Initiative
Whereas bleeding complications requiring a return to the operating room (OR) after carotid endarterectomy (CEA) are infrequent (1%), they are associated with an increased 30-day combined postoperative stroke or death rate. Drain placement after CEA varies among vascular surgeons, and there are limited data to support the practice. The goal of this study was to evaluate factors leading to drain placement and the effect of drains on postoperative outcomes including return to OR for bleeding, stroke, and death.
Source: Journal of Vascular Surgery - February 11, 2020 Category: Surgery Authors: Christopher J. Smolock, Katherine L. Morrow, Jeanwan Kang, Rebecca L. Kelso, James F. Bena, Daniel G. Clair Source Type: research
Vorapaxar in Patients With Peripheral Artery Disease: Results from TRA2°P-TIMI 50
Vorapaxar does not decrease the risk of cardiovascular death, stroke, or myocardial infarction in patients with peripheral artery disease (PAD). It does result in reduced limb ischemia and reduced peripheral revascularization. The benefits on limb vascular events were accompanied by an increased risk of bleeding.
Source: Journal of Vascular Surgery - August 28, 2013 Category: Surgery Authors: M.P. Bonaca, B.M. Scirica, M.A. Craeger Tags: Abstracts Source Type: research
Aspirin responsiveness safely lowers perioperative cardiovascular risk
Conclusions: The degree of aspirin effect on platelet aggregability maybe important in the management of perioperative CV morbidity, without increment in the bleeding toll.
Source: Journal of Vascular Surgery - November 28, 2013 Category: Surgery Authors: Daniela Calderaro, Adriana Feio Pastana, Tania Rubia Flores da Rocha, Pai Ching Yu, Danielle Menosi Gualandro, Nelson DeLuccia, Élbio Antônio D`Amico, Bruno Caramelli Tags: Clinical research studies Source Type: research
Dual antiplatelet therapy reduces stroke but increases bleeding at the time of carotid endarterectomy
This study examined the effect of preoperative dual antiplatelet therapy (aspirin and clopidogrel) on in-hospital CEA outcomes.
Source: Journal of Vascular Surgery - February 28, 2016 Category: Surgery Authors: Douglas W. Jones, Philip P. Goodney, Mark F. Conrad, Brian W. Nolan, Eva M. Rzucidlo, Richard J. Powell, Jack L. Cronenwett, David H. Stone Tags: Clinical paper Source Type: research
Invited commentary
The key findings were that adding clopidogrel to regular aspirin therapy ≤48 hours of carotid endarterectomy (CEA) was associated with significant reductions in postoperative stroke, at the expense of increased bleeding complications.1 The latter will, inevitably, reinforce certain prejudices regarding dual-antiplatelet therapy (DAPT), even though the rate of bleeding complications was only 1.2% (DAPT) vs 0.7% (monotherapy). However, before uncritically disregarding any role for DAPT, it is worth considering why this debate is so important.
Source: Journal of Vascular Surgery - April 21, 2016 Category: Surgery Authors: A. Ross Naylor Tags: Clinical research study Source Type: research
Use of Protamine for Anticoagulation During Carotid Endarterectomy: A Meta-Analysis
Use of protamine following carotid endarterectomy (CEA) is associated with a reduction in bleeding complications without increasing major thrombotic outcomes of stroke, myocardial infarction or death.
Source: Journal of Vascular Surgery - May 23, 2016 Category: Surgery Authors: K.A. Newhall, E.C. Saunders, R.J. Larson Tags: Abstract Source Type: research
Protamine Reduces Bleeding Complications without Increasing the Risk of Stroke after Carotid Endarterectomy: A Meta-analysis
The aim was to evaluate the safety and efficacy of heparin reversal with protamine after completion of carotid endarterectomy (CEA), summarising the available data from both randomised and non-randomised studies.
Source: Journal of Vascular Surgery - September 22, 2016 Category: Surgery Authors: J.D. Kakisis, C.N. Antonopoulos, K.G. Moulakakis, F. Schneider, G. Geroulakos, J.B. Ricco Tags: Selected abstract from the September issue of the European Journal of Vascular and Endovascular Surgery Source Type: research
Systematic Review and Meta-Analysis of Dual Versus Single Antiplatelet Therapy in Carotid Interventions
Dual antiplatelet therapy demonstrates advantages over single therapy only in patients treated with a carotid artery stent as determined by a decrease risk of transient ischemia attack. Dual therapy was associated with an increased risk of major bleeding, neck hematoma and MI in those undergoing carotid endarterectomy with no benefit regarding protection from transient ischemic attack (TIA)/stroke/mortality.
Source: Journal of Vascular Surgery - February 22, 2017 Category: Surgery Authors: M. Barkat, S. Hajibandeh, S. Hajibandeh, F. Torella, G.A. Antoniou Tags: Abstract Source Type: research
