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Source: Clinical Research in Cardiology
Condition: Bleeding

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Total 64 results found since Jan 2013.

Blood pressure and prognosis in patients with incident heart failure: the Diet, Cancer and Health (DCH) cohort study
Conclusion We have shown for the first time that amongst a population with incident HF, higher baseline systolic, diastolic and pulse pressure levels were associated with a higher rate of adverse events. Our data support the importance for optimised BP control, as part of the holistic management of HF patients.
Source: Clinical Research in Cardiology - June 26, 2015 Category: Cardiology Source Type: research

Non-vitamin K antagonist oral anticoagulants in the cardioversion of patients with atrial fibrillation: systematic review and meta-analysis
Conclusions This systematic review and meta-analysis suggests that NOACs may be as safe as VKAs in the setting of AF cardioversion.
Source: Clinical Research in Cardiology - February 3, 2015 Category: Cardiology Source Type: research

Renal function and non-vitamin K oral anticoagulants in comparison with warfarin on safety and efficacy outcomes in atrial fibrillation patients: a systemic review and meta-regression analysis
Conclusion Non-vitamin K oral anticoagulants had similar efficacy and safety compared to warfarin across different levels of renal function. Indirect comparisons suggest that apixaban and edoxaban were associated with a better safety profile in patients with moderate renal impairment. However, caution is warranted when interpreting indirect comparisons of drugs investigated in different trials. Prescribers should fit the most appropriate NOAC to the AF patient characteristics (and vice versa) to individualise effective stroke prevention.
Source: Clinical Research in Cardiology - November 21, 2014 Category: Cardiology Source Type: research

Adherence to warfarin treatment among patients with atrial fibrillation
Conclusions Adherence to treatment with warfarin can be estimated on group level from prescription data and may be useful for comparison of adherence with warfarin and new oral anticoagulants. When applied to a large warfarin-treated cohort with atrial fibrillation, we found that adherence is low and that measures aiming for improvements are needed .
Source: Clinical Research in Cardiology - November 17, 2014 Category: Cardiology Source Type: research