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Efficacy of ablation therapy on clinical outcomes in patients with atrial fibrillation: a systematic review and meta-analysis
CONCLUSION: Ablation significantly reduces the risk of stroke, cardiovascular mortality, all-cause mortality, and HF in AF patients, compared with medical therapy alone, supporting its use in clinical practice.PMID:37663739 | PMC:PMC10473299 | DOI:10.1097/MS9.0000000000000985
Source: Annals of Medicine - September 4, 2023 Category: Internal Medicine Authors: Mohammad Munim Zahoor Saad Ehsan Ullah Harriet Mmaitsi Kidiavai Shahda A H Eltieb Anjuli Devi Muhammad Anis Asif Akshay Vaswani Ammar Hyder Muhammad Roshan Hoti Sayed Jawad Sana Arshid Abhirami Shankar Muhammad Salman Source Type: research

Efficacy and safety of direct oral anticoagulants vs vitamin K antagonists in patients with atrial fibrillation and end-stage renal disease on hemodialysis: A systematic review and meta-analysis
CONCLUSIONS: Among AF patients with ESRD on chronic hemodialysis, the risk of ischemic stroke, ischemic stroke or systemic embolism, minor bleeding, major bleeding, and all-cause mortality is similar in patients treated with DOACs compared to VKAs. Given that the meta-analysis of RCTs on gastrointestinal bleeding did not confirm the results of the meta-analysis of the observational studies, it cannot be concluded that gastrointestinal bleeding is lower among DOAC-treated patients.PROTOCOL REGISTRATION: PROSPERO CRD42023391966.PMID:37648582 | DOI:10.1016/j.ejim.2023.08.020
Source: European Journal of Internal Medicine - August 30, 2023 Category: Internal Medicine Authors: Ioannis Kyriakoulis Anastasia Adamou Iliana Stamatiou David Dimitris Chlorogiannis Ioannis Kardoutsos Despoina Koukousaki George Ntaios Source Type: research

Incidence of Arterial Thrombotic and Bleeding Events in Patients Who Develop Cancer After ST-elevation Myocardial Infarction
Conclusion Cancers increase unpredictable bleeding but not arterial thrombotic events in patients after STEMI.PMID:37612081 | DOI:10.2169/internalmedicine.2385-23
Source: Internal Medicine - August 23, 2023 Category: Internal Medicine Authors: Toshiharu Fujii Yuji Ikari Source Type: research

The Combinations of the Patterns of Non-Adherence to Anti-Platelet Regimen in Stented Patients (PARIS) and Coronary Revascularization Demonstrating Outcome Study in Kyoto (CREDO-Kyoto) Thrombotic and Bleeding Risk Scores on Clinical Outcomes in Patients with Acute Myocardial Infarction
Conclusion The combinations of the PARIS and CREDO-Kyoto risk scores might be useful for evaluating ischemic and bleeding risks in patients with acute MI undergoing primary PCI.PMID:37344423 | DOI:10.2169/internalmedicine.2117-23
Source: Internal Medicine - June 21, 2023 Category: Internal Medicine Authors: Daichi Yamashita Yuichi Saito Takanori Sato Tadahiro Matsumoto Sakuramaru Suzuki Kan Saito Shinichi Wakabayashi Hideki Kitahara Koichi Sano Yoshio Kobayashi Source Type: research

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