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Protamine Reduces Serious Bleeding Complications Associated with Carotid Endarterectomy in Asymptomatic Patients without Increasing the Risk of Stroke, Myocardial Infarction, or Death in a Large National Analysis.
CONCLUSION: Protamine reduces serious bleeding complications at the time of CEA without increasing the risk of MI, stroke, or death, in this large North American analysis. Based on this and previous regional work regarding protamine use in CEA, it is believed that there is now sufficient evidence to support its routine use, and it should be considered as a benchmark for quality during CEA. PMID: 33127243 [PubMed - as supplied by publisher]
Source: PubMed: Eur J Vasc Endovasc ... - October 27, 2020 Category: Surgery Authors: Stone DH, Giles KA, Kubilis P, Suckow BD, Goodney PP, Huber TS, Powell RJ, Cronenwett JL, Scali ST Tags: Eur J Vasc Endovasc Surg Source Type: research

Protamine Reduces the Risk of Serious Bleeding at the Time of CEA without Increased Risk of Stroke, MI or Death
Introduction: Controversy persists regarding the use of Protamine during carotid endarterectomy (CEA) despite real world evidence to support its use. The purpose of this study was to best determine the impact of protamine reversal of heparin anticoagulation on the outcome of CEA throughout the United States.
Source: European Journal of Vascular and Endovascular Surgery - November 30, 2019 Category: Surgery Authors: David Stone, Kristina Giles, Bjoern Suckow, Philip Goodney, Thomas Huber, Richard Powell, Jack Cronenwett, Salvatore Scali Source Type: research

Carotid artery stenting without using any embolic protective device A single Centre experience.
CONCLUSION: Revascularisation interventions to be able to prevent the development of stroke are evaluated as important treatment options in patients with symptomatic or severe carotid stenosis. With careful patient selection in experienced centres and a multi-disciplinary approach both before and after the procedure, pleasing results can be obtained without the use of embolic protective devices. KEY WORDS: Carotid artery stenting, Embolic protective device, Stroke. PMID: 30665216 [PubMed - in process]
Source: Annali Italiani di Chirurgia - January 23, 2019 Category: Surgery Tags: Ann Ital Chir Source Type: research