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< em > In-vitro < /em > antioxidant, lipoxygenase inhibitory, and < em > in-vivo < /em > muscle relaxant potential of the extract and constituent isolated from < em > Diospyros kaki < /em > (Japanese Persimmon)
This study excellently rationalizes the traditional usage of D. kaki in curing various diseases. Furthermore, the docking results indicate, that the isolated compound fits well into the active site of the lipoxygenase, and makes strong interactions with the target protein.PMID:36895410 | PMC:PMC9989937 | DOI:10.1016/j.heliyon.2023.e13816
Source: Atherosclerosis - March 10, 2023 Category: Cardiology Authors: Adil Mujawah Abdur Rauf Sami Bawazeer Abdul Wadood Hassan A Hemeg Saud Bawazeer Source Type: research

Predictors of Intensive Care Unit Admission in Patients with Confirmed Coronavirus Disease 2019: A Cross-Sectional Study
CONCLUSION: A high index of suspicion for ICU admission should be maintained in patients with positive clinical and laboratory predictive factors.PMID:36117577 | PMC:PMC9445874 | DOI:10.30476/IJMS.2021.89916.2068
Source: Atherosclerosis - September 19, 2022 Category: Cardiology Authors: Naeimehossadat Asmarian Farid Zand Parvin Delavari Vahid Khaloo Zahra Esmaeilinezhad Golnar Sabetian Yaldasadat Moeini Mohsen Savaie Fatemeh Javaherforooshzadeh Farhad Soltani Farid Yousefi Ebrahim Heidari Sardabi Maryam Haddadzadeh Shoushtari Anoush Dehn Source Type: research

Young mother with lupus and life-altering cardiocerebrovascular nightmare: a case report
CONCLUSION: Recognizing and anticipating gender-specific issues in managing patients with SLE are keys to preventing catastrophic complications. Multi-disciplinary team involvement is critical in dealing with complex cases.PMID:35898406 | PMC:PMC9311826 | DOI:10.1093/ehjcr/ytac293
Source: Atherosclerosis - July 28, 2022 Category: Cardiology Authors: Indah Sukmawati Agatha Christiani Sandra Sinthya Langow Antonia Anna Lukito Source Type: research

Thrombotic Complications of COVID-19 Infection: A Review
The novel coronavirus (severe acute respiratory syndrome CoV-2 [SARS-CoV-2]), also known as COVID-19, is a single-stranded enveloped RNA virus that created a Public Health Emergency of International Concern in January 2020, with a global case burden of over 15 million in just 7 months. Infected patients develop a wide range of clinical manifestations—typically presenting with fever, cough, myalgia, and fatigue. Severely ill patients may fall victim to acute respiratory distress syndrome, acute heart injuries, neurological manifestations, or complications due to secondary infections. These critically ill patients are also...
Source: Cardiology in Review - December 13, 2020 Category: Cardiology Tags: Review Articles Source Type: research

Diastolic dysfunction reduces stroke volume during daily's life activities in patients with severe aortic stenosis
Pathophysiologic consequences of left ventricular (LV) hypertrophy and fibrosis, as these occur in aortic stenosis, are elevated filling and left atrial (LA) pressures [1]. Depending on the time duration of pressure overload, LA volume increases proportionally to the degree of left ventricular (LV) diastolic dysfunction [2]. Elevated LA pressure aims to ensure adequate LV filling and, consequently, stroke volume but may return to normal levels during certain daily activities (e.g., cough, defecation, lifting a heavy or even medium load), which produce a preload reduction, possibly compromising LV both filling and stroke volume [1].
Source: International Journal of Cardiology - May 20, 2015 Category: Cardiology Authors: Maria Angela Losi, Raffaele Izzo, Eugenio Stabile, Anna Sannino, Grazia Canciello, Alessandra Giamundo, Francesca Musella, Plinio Cirillo, Mariella Prastaro, Maurizio Galderisi, Bruno Trimarco, Giovanni Esposito Tags: Letter to the Editor Source Type: research

Challenges in the management of hypertension in Asia
Hypertension is common in Asian populations and is a major cause of cardiovascular diseases. Even a small reduction in blood pressure can lead to a substantial decrease in the risk of stroke. The prevalence of hypertension appears to be increasing in many countries, partly because of ageing of the population, but also because of increasing obesity. While much effort has gone into promoting the awareness of hypertension, the rates of detection, treatment, and control remain low. As hypertension is very prevalent in the general population, it makes sense to adopt population approaches towards the detection and treatment of h...
Source: European Journal of Heart Failure Supplements - February 23, 2012 Category: Cardiology Authors: Cheung, B. M. Y., Cheung, T. T. Tags: Original Articles Source Type: research