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Total 318 results found since Jan 2013.
E-132 Successful mechanical thrombectomy in an 11-year-old patient with emergent large vessel occlusion acute ischemic stroke related to congenital complete heart block and recent covid-19 infection
ConclusionsThis is a first known report of a successful mechanical thrombectomy in a pediatric patient due to a large vessel occlusion related to congenital complete heart block and recent COVID-19 infection.Disclosures J. Ansari: None. D. Mata Canadas: None. M. Ayub: None. J. Caskey: None. P. Simoncini: None. R. Riel-Romero: None. P. Sharma: None. D. Jordan: None. H. Cuellar: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Ansari, J., Mata Canadas, D., Ayub, M., Caskey, J., Simoncini, P., Riel-Romero, R., Sharma, P., Jordan, D., Cuellar, H. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research
Screening for silent aspiration in hyperacute stroke: A feasibility study of clinical swallowing examination and cough reflex testing
CONCLUSIONS & IMPLICATIONS: CRT, CSE and FEES are feasible in 58% of hyperacute stroke patients in this setting. FEES anxiety is the main recruitment barrier and is not always well tolerated. Results support further work to establish optimum methods and differential sensitivity/specificity of CRT and CSE in hyperacute stroke for SA identification.WHAT THIS PAPER ADDS: What is already known on this subject SA significantly increases the risk of pneumonia in the early days post-stroke. CSEs are unreliable for identification of SA risk in this population. CRT is gaining popularity as a potential tool to identify stroke patien...
Source: International Journal of Language and Communication Disorders - May 9, 2023 Category: Speech-Language Pathology Authors: Julie Trimble Joanne M Patterson Janet A Wilson Anand K Dixit Michael Drinnan Source Type: research
New paradigms in purinergic receptor ligand discovery
Neuropharmacology. 2023 Mar 13:109503. doi: 10.1016/j.neuropharm.2023.109503. Online ahead of print.ABSTRACTThe discovery and clinical implementation of modulators of adenosine, P2Y and P2X receptors have progressed dramatically in ∼50 years since Burnstock's definition of purinergic signaling. Although most clinical trials of selective ligands (agonists and antagonists) of these nineteen receptors failed, there is a renewed impetus to redirect efforts to new disease conditions and the discovery of more selective or targeted compounds with potentially reduced side effects, such as biased GPCR agonists. The elucidation of...
Source: Neuropharmacology - March 15, 2023 Category: Drugs & Pharmacology Authors: Kenneth A Jacobson Balaram Pradhan Zhiwei Wen Asmita Pramanik Source Type: research
< em > In-vitro < /em > antioxidant, lipoxygenase inhibitory, and < em > in-vivo < /em > muscle relaxant potential of the extract and constituent isolated from < em > Diospyros kaki < /em > (Japanese Persimmon)
This study excellently rationalizes the traditional usage of D. kaki in curing various diseases. Furthermore, the docking results indicate, that the isolated compound fits well into the active site of the lipoxygenase, and makes strong interactions with the target protein.PMID:36895410 | PMC:PMC9989937 | DOI:10.1016/j.heliyon.2023.e13816
Source: Atherosclerosis - March 10, 2023 Category: Cardiology Authors: Adil Mujawah Abdur Rauf Sami Bawazeer Abdul Wadood Hassan A Hemeg Saud Bawazeer Source Type: research
Letter to the Editor on: Respiratory Muscle Training Reduces Respiratory Complications and Improves Swallowing Function After Stroke: A Systematic Review and Meta-analysis
We read with great interest the article titled “Respiratory Muscle Training Reduces Respiratory Complications and Improves Swallowing Function After Stroke: A Systematic Review and Meta-Analysis,” published in the recent issue of the Arch Phys Med Rehabil.1 This paper summarized the available evidence to assess whether respiratory muscle tra ining could reduce respiratory complications in patients after stroke. The authors concluded that respiratory muscle training was effective in reducing the risk of respiratory complications and improving swallowing function; however, no significant effect of the exercise on cough f...
Source: Archives of Physical Medicine and Rehabilitation - March 9, 2023 Category: Rehabilitation Authors: Junfang He, Xu Cheng Tags: LETTER TO THE EDITOR Source Type: research
Comment on: Respiratory Muscle Training Reduces Respiratory Complications and Improves Swallowing Function After Stroke: A Systematic Review and Meta-Analysis
We read with great interest the article titled "Respiratory Muscle Training Reduces Respiratory Complications and Improves Swallowing Function After Stroke: A Systematic Review and Meta-Analysis" published in the recent issue of the Arch Phys Med Rehabil.1 This paper summarized the available evidence to assess whether respiratory muscle training could reduce respiratory complications in patients after stroke. The authors concluded that respiratory muscle training was effective in reducing the risk of respiratory complications and improving swallowing function; however, no significant effect of the exercise on cough function was observed.
Source: Archives of Physical Medicine and Rehabilitation - March 9, 2023 Category: Rehabilitation Authors: Junfang He, Xu Cheng Tags: Letter to the Editor Source Type: research
Case report: Dysphagia after COVID-19 infection in a stroke patient —Is neurostimulation a potential management?
A 90-year-old man with stroke was weaned from tube feeding 4 months after stroke onset. However, he had a coronavirus disease 2019 (COVID-19) infection after 2 months and suffered from drastically worsened oropharyngeal dysphagia that required a reinsertion of the nasogastric tube. A videofluoroscopic swallowing study revealed poor bolus oral transit, significantly delayed swallowing reflex, reduced pharyngeal movements, and insufficient cough response. Repetitive transcranial magnetic stimulation and neuromuscular electrical stimulation were applied, in addition to conventional swallowing training. The feeding tube was re...
Source: Frontiers in Neurology - March 6, 2023 Category: Neurology Source Type: research
New VOYAGER PAD Analysis Confirms Consistent Benefit of XARELTO ® (rivaroxaban) Plus Aspirin Following Lower Extremity Revascularization (LER)
TITUSVILLE, NJ, March 5, 2023 – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced data from a new prespecified analysis from the Phase 3 VOYAGER PAD clinical trial reinforcing the benefits of the XARELTO® (rivaroxaban) vascular dose (2.5 mg twice daily plus aspirin 100 mg once daily) over standard of care (aspirin alone), demonstrating consistent benefit at 30 days, 90 days and up to three years following LER in patients with PAD. Lower extremity revascularization, also called peripheral revascularization, is a procedure that restores blood flow in blocked arteries or veins. This analysis of ...
Source: Johnson and Johnson - March 5, 2023 Category: Pharmaceuticals Tags: Latest News Source Type: news
SARS-CoV-2 neurotropism and other possible causes of olfactory disorders in COVID-19
Neurol Neurochir Pol. 2023 Feb 20. doi: 10.5603/PJNNS.a2023.0013. Online ahead of print.ABSTRACTCoronavirus disease 2019 (COVID-19) is an acute infectious respiratory disease (AIRD) caused by infection with the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The first cases were diagnosed and reported in Wuhan, central China, in November 2019. The disease initially occurred locally. However, the number of infected individuals increased dynamically and spread worldwide. The most common symptoms of the SARS-CoV-2 infection include malaise, fever, dry cough and dyspnoea. Over time, reports of new COVID-19 sy...
Source: Neurologia i Neurochirurgia Polska - February 22, 2023 Category: Neurology Authors: Pawe ł Sowa Adam Dadok Monika Adamczyk-Sowa Source Type: research
