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Specialty: Drugs & Pharmacology
Condition: Arthritis
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Total 30 results found since Jan 2013.
Interpersonal Values of Patients Participating in Phase II –III Clinical Trials: Implications for Clinical Trial Representativeness
ConclusionsThis novel analysis of the interpersonal values of patients that participate in Phase II and III clinical trials revealed that the patients ’ interpersonal values largely differed from those of the Portuguese normative population. Better understanding the implications of these findings for clinical trial representativeness and outcomes is of crucial importance.
Source: Pharmaceutical Medicine - May 30, 2023 Category: Drugs & Pharmacology Source Type: research
The effect of statin on major adverse cardiovascular events and mortality in patients with rheumatoid arthritis - a systematic review and meta-analysis
CONCLUSIONS: This systematic review and meta-analysis showed that statin was associated with reduction of MACE and mortality in patients with RA.PMID:35587067 | DOI:10.26355/eurrev_202205_28734
Source: Pharmacological Reviews - May 19, 2022 Category: Drugs & Pharmacology Authors: A R Rahmadi R Pranata W M Raffaello E Yonas M P Ramadhian M R R Natadikarta M R Akbar Source Type: research
Mechanism of Dihydromyricetin on Inflammatory Diseases
Inflammation plays a crucial role in a variety of diseases, including diabetes, arthritis, asthma, Alzheimer’s disease (AD), acute cerebral stroke, cancer, hypertension, and myocardial ischemia. Therefore, we need to solve the problem urgently for the study of inflammation-related diseases. Dihydromyricetin (DHM) is a flavonoid mainly derived from Nekemias grossedentata (Hand.-Mazz.) J.Wen and Z.L.Nie (N.grossedentata). DHM possesses many pharmacological effects, including anti-inflammatory (NLRP-3, NF-κB, cytokines, and neuroinflammation), antioxidant, improving mitochondrial dysfunction, and regulating autophagy and s...
Source: Frontiers in Pharmacology - January 18, 2022 Category: Drugs & Pharmacology Source Type: research
Risk of thromboembolic events and associated risk factors, including treatments, in patients with immune-mediated diseases
This study assessed the association between thromboembolic events (TEs) and immune-mediated diseases (IMDs) and characterized the risk profile of TEs among patients with IMDs.METHODS: An administrative claims database (2014-2018) was used to identify adults with ≥2 diagnoses on different dates for ≥1 IMD (IMD cohort; ankylosing spondylitis, atopic dermatitis, inflammatory bowel disease, multiple sclerosis, psoriasis, psoriatic arthritis, rheumatoid arthritis, and systemic lupus erythematosus); patients without an IMD diagnosis were assigned to the non-IMD cohort. Patients in the IMD cohort were matched 1:1 to patients ...
Source: Clinical Therapeutics - July 9, 2021 Category: Drugs & Pharmacology Authors: Juliana Setyawan Fan Mu Andres Yarur Miriam L Zichlin Hongbo Yang Catherine Fernan Emma Billmyer Nathaniel Downes Nassir Azimi Vibeke Strand Source Type: research
