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miR ‑183‑5p attenuates cerebral ischemia injury by negatively regulating PTEN.
miR‑183‑5p attenuates cerebral ischemia injury by negatively regulating PTEN. Mol Med Rep. 2020 Sep 07;: Authors: Zhu L, Zhou X, Li S, Liu J, Yang J, Fan X, Zhou S Abstract Cerebral ischemia is a common cerebrovascular disease caused by the occlusion of a cerebral blood vessel. MicroRNAs (miRNAs/miRs) are emerging regulators of various human diseases, including cerebral ischemia. Upregulation of miR‑183‑5p has been reported to alleviate liver injury induced by ischemia‑reperfusion (I/R). However, the effect of miR‑183‑5p on cerebral ischemia injury remains unknown. The present study evalu...
Source: Molecular Medicine Reports - September 10, 2020 Category: Molecular Biology Tags: Mol Med Rep Source Type: research

Fibrinogen nitrotyrosination after ischemic stroke impairs thrombolysis and promotes neuronal death
Publication date: Available online 12 December 2014 Source:Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease Author(s): Gerard ILL-Raga , Ernest Palomer , Eva Ramos-Fernández , Francesc X. Guix , Mònica Bosch-Morató , Biuse Guivernau , Marta Tajes , Victòria Valls-Comamala , Jordi Jiménez-Conde , Angel Ois , Fernando Pérez-Asensio , Mario Reyes-Navarro , Carolina Caballo , Gabriel Gil-Gómez , Irene López-Vílchez , Ana M. Galán , Francesc Alameda , Ginés Escolar , Carlos Opazo , Anna Planas , Jaume Roquer , Miguel A. Valverde , Francisco J. Muñoz Ischemic stroke is an acute vascular event that c...
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - December 25, 2014 Category: Molecular Biology Source Type: research