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Condition: Multiple Sclerosis
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Total 143 results found since Jan 2013.

Microbiota, diet and the gut-brain axis in multiple sclerosis and acute stroke
This article is protected by copyright. All rights reserved.PMID:37470461 | DOI:10.1002/eji.202250229
Source: European Journal of Immunology - July 20, 2023 Category: Allergy & Immunology Authors: Laura Diaz-Marugan Johan B Kantsj ö Andrina Rutsch Francesca Ronchi Source Type: research

Can ‘toxic’ bilirubin treat a variety of illnesses?
Generations of medical and biology students have been instilled with a dim view of bilirubin. Spawned when the body trashes old red blood cells, the molecule is harmful refuse and a sign of illness. High blood levels cause jaundice, which turns the eyes and skin yellow and can signal liver trouble. Newborns can’t process the compound, and although high levels normally subside, a persistent surplus can cause brain damage. Yet later this year up to 40 healthy Australian volunteers may begin receiving infusions of the supposedly good-for-nothing molecule. They will be participating in a phase 1 safety trial, sponsored ...
Source: ScienceNOW - June 8, 2023 Category: Science Source Type: news

Interpersonal Values of Patients Participating in Phase II –III Clinical Trials: Implications for Clinical Trial Representativeness
ConclusionsThis novel analysis of the interpersonal values of patients that participate in Phase II and III clinical trials revealed that the patients ’ interpersonal values largely differed from those of the Portuguese normative population. Better understanding the implications of these findings for clinical trial representativeness and outcomes is of crucial importance.
Source: Pharmaceutical Medicine - May 30, 2023 Category: Drugs & Pharmacology Source Type: research

Primary healthcare needs and service utilisation of people with disability: a data linkage protocol
Introduction General practitioners (GPs) play a crucial role in the early management and treatment of the comorbidities and complications experienced by people with disability. However, GPs experience multiple constraints, including limited time and disability-related expertise. Knowledge gaps around the health needs of people with disability as well as the frequency and extent of their engagement with GPs mean evidence to inform practice is limited. Using a linked dataset, this project aims to enhance the knowledge of the GP workforce by describing the health needs of people with disability. Methods and analysis This pro...
Source: BMJ Open - April 19, 2023 Category: General Medicine Authors: Douglas, J., Winkler, D., McLeod, A., Oliver, S., Gardner, K., Supple, J., Pearce, C. Tags: Open access, Health services research Source Type: research

Fatigue and its relation to general cognition, social cognition and social activity in multiple sclerosis and stroke
CONCLUSIONS: Future studies ought to further explore the potentially complex nature of fatigue symptoms and their relationship with (socio-)cognitive performance and social activity in neurological populations.PMID:36782396 | DOI:10.1080/13546805.2023.2178399
Source: Cognitive Neuropsychiatry - February 14, 2023 Category: Psychiatry Authors: Tobias Lohaus Judith Witt Anne Sch ürmeyer Oliver T Wolf Patrizia Thoma Source Type: research