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Drug: Docetaxel
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Total 2210 results found since Jan 2013.
Synthesis of Au-Ag bimetallic nanoparticles using Korean red ginseng (Panax ginseng Meyer) root extract for chemo-photothermal anticancer therapy
Arch Pharm Res. 2023 Aug 17. doi: 10.1007/s12272-023-01457-y. Online ahead of print.ABSTRACTGreen synthesis strategies have been widely applied for the preparation of versatile nanomaterials. Gold nanospheres with an average size of 6.95 ± 2.25 nm were green synthesized by using a 70% ethanol extract of Korean red ginseng (Panax ginseng Meyer) root as a reducing agent. A seed-mediated synthesis was conducted to prepare Au-Ag bimetallic nanoparticles using gold nanospheres as seeds. Remarkably, Au-Ag bimetallic nanoparticles with an average size of 80.4 ± 11.9 nm were synthesized. Scanning transmission electron microscopy...
Source: Archives of Pharmacal Research - August 17, 2023 Category: Drugs & Pharmacology Authors: Gayeon Lee You Jeong Lee Yeon-Jeong Kim Youmie Park Source Type: research
Hypersensitivity Reactions to Taxanes: A Comprehensive and Systematic Review of the Efficacy and Safety of Desensitization
AbstractTaxanes in the treatment of cancer are associated with a significant incidence of hypersensitivity reactions, which may preclude their use in patients in need of first line therapy. Drug desensitization induces transient immunological tolerance and has allowed the reintroduction of taxanes in highly allergic patients. Increase the knowledge of hypersensitivity reactions (HSR) during the administration of taxanes. A systematic review regarding the safety and efficacy of rapid drug desensitization (RDD) for taxanes HSR. The study followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)...
Source: Clinical Reviews in Allergy and Immunology - August 17, 2023 Category: Allergy & Immunology Source Type: research
Randomized Phase II Multicenter Trial of Abiraterone Acetate With or Without Cabazitaxel in the Treatment of Metastatic Castration-Resistant Prostate Cancer
CONCLUSION: AAP + C was safe with improved rPFS, OS duration, and a higher proportion of PSA declines. This suggests that AAP + C given earlier rather than sequentially may benefit some men. Further work is needed to identify this population.PMID:37582240 | DOI:10.1200/JCO.22.02639
Source: Clinical Prostate Cancer - August 15, 2023 Category: Cancer & Oncology Authors: Susan F Slovin Karen Knudsen Susan Halabi Renee de Leeuw Ayesha Shafi Praneet Kang Steven Wolf Bin Luo Anuradha Gopalan Tracy Curley Mark Fleming Ana Molina Celina Fernandez Kevin Kelly Source Type: research
Integrated Multimodal Analyses of DNA Damage Response and Immune Markers as Predictors of Response in Metastatic Triple-Negative Breast Cancer in the TNT Trial (NCT00532727)
CONCLUSIONS: High immune features predict docetaxel response, and high DDR signature scores predict carboplatin response in treatment-naïve mTNBC. Integrating multimodal DDR and immune-related markers identifies subgroups with differential treatment sensitivity. Treatment options for patients with immune-low and DDR-proficient tumors remains an outstanding need. Caution is needed using PT-derived transcriptional signatures to direct treatment in mTNBC, particularly DDR-related markers following prior chemotherapy.PMID:37574209 | DOI:10.1158/1078-0432.CCR-23-0370
Source: Clinical Cancer Research - August 13, 2023 Category: Cancer & Oncology Authors: Holly Tovey Orsolya Sipos Joel S Parker Katherine A Hoadley Jelmar Quist Sarah Kernaghan Lucy Kilburn Roberto Salgado Sherene Loi Richard D Kennedy Ioannis Roxanis Patrycja Gazinska Sarah E Pinder Judith Bliss Charles M Perou Syed Haider Anita Grigoriadis Source Type: research
