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The effect of bladder function on the efficacy of transurethral prostatectomy in patients with benign prostatic hyperplasia: a retrospective, single-center study
Asian J Androl. 2023 Aug 11. doi: 10.4103/aja202327. Online ahead of print.ABSTRACTWe investigated the impact and predictive value of bladder function in patients with benign prostatic hyperplasia (BPH) on the efficacy of transurethral prostatectomy. Symptomatic, imaging, and urodynamic data of patients who underwent transurethral prostatectomy at West China Hospital of Sichuan University (Chengdu, China) from July 2019 to December 2021 were collected. Follow-up data included the quality of life (QoL), International Prostate Symptom Score (IPSS), and IPSS storage and voiding (IPSS-s and IPSS-v). Moreover, urinary creatinin...
Source: Asian Journal of Andrology - August 18, 2023 Category: Urology & Nephrology Authors: Jin Li Xian-Yan-Ling Yi Ze-Yu Chen Bo Chen Yin Huang Da-Zhou Liao Pu-Ze Wang De-Hong Cao Jian-Zhong Ai Liang-Ren Liu Source Type: research

Endothelial ER α promotes glucose tolerance by enhancing endothelial insulin transport to skeletal muscle
Nat Commun. 2023 Aug 17;14(1):4989. doi: 10.1038/s41467-023-40562-w.ABSTRACTThe estrogen receptor (ER) designated ERα has actions in many cell and tissue types that impact glucose homeostasis. It is unknown if these include mechanisms in endothelial cells, which have the potential to influence relative obesity, and processes in adipose tissue and skeletal muscle that impact glucose control. Here we show that independent of impact on events in adipose tissue, endothelial ERα promotes glucose tolerance by enhancing endothelial insulin transport to skeletal muscle. Endothelial ERα-deficient male mice are glucose intolerant...
Source: Cancer Control - August 17, 2023 Category: Cancer & Oncology Authors: Anastasia Sacharidou Ken Chambliss Jun Peng Jose Barrera Keiji Tanigaki Katherine Luby-Phelps İpek Özdemir Sohaib Khan Shashank R Sirsi Sung Hoon Kim Benita S Katzenellenbogen John A Katzenellenbogen Mohammed Kanchwala Adwait A Sathe Andrew Lemoff Chao Source Type: research

The dose-dependent effect of estrogen on bone mineral density in trans girls
CONCLUSION: Higher estrogen dosage is associated with a greater increase in lumbar spine BMD Z-scores. Increasing dosage up to 2mg estradiol is insufficient to optimize BMD and approximately 4 mg may be required for adequate serum concentrations.PMID:37590955 | DOI:10.1093/ejendo/lvad116
Source: European Journal of Endocrinology - August 17, 2023 Category: Endocrinology Authors: Lidewij Sophia Boogers Maria Anna Theodora Catharina van der Loos Chantal Maria Wiepjes Adrianus Sarinus Paulus van Trotsenburg Martin den Heijer Sabine Elisabeth Hannema Source Type: research