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Infectious Disease: Herpes

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Short nucleotide sequences in herpesviral genomes identical to the human DNA
Publication date: 7 May 2015 Source:Journal of Theoretical Biology, Volume 372 Author(s): Felix Filatov , Alexander Shargunov In 2010, we described many similar DNA sequences in human and viral genomes, including herpesviral ones. The data obtained allowed us to suggest that these motifs may provide the antiviral protection by mating with a complementary potential target and destroying it by the catalytic way like small interfering RNA, siRNA. Since we have analyzed these viruses as a group, two major issues seemed to us curious: (1) the number of such motifs in genomes of various herpesvirus types, and (2) distribution ...
Source: Journal of Theoretical Biology - March 12, 2015 Category: Biology Source Type: research