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In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy
Cell Death & Disease, Published online: 22 September 2023; doi:10.1038/s41419-023-06159-3In vivo self-assembly and delivery of VEGFR2 siRNA-encapsulated small extracellular vesicles for lung metastatic osteosarcoma therapy
Source: Cell death and disease - September 22, 2023 Category: Internal Medicine Authors: Lingfeng Yu Gentao Fan Qingyan Wang Yan Zhu Hao Zhu Jiang Chang Zhen Wang Shoubin Zhan Xianming Hua Diankun She Jianhao Huang Yicun Wang Jianning Zhao Chen-Yu Zhang Xi Chen Guangxin Zhou Source Type: research

In vitro effect of microRNA-107 targeting Dkk-1 by regulation of Wnt/β-catenin signaling pathway in osteosarcoma
Conclusion: We conclude that miR-107 is likely to inhibit the occurrence and development of OS by down-regulating Dkk-1 via the Wnt/β-catenin signaling pathway, providing us with a new therapeutic target for the treatment of OS.
Source: Medicine - July 1, 2017 Category: Internal Medicine Tags: Research Article: Clinical Trial/Experimental Study Source Type: research