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Cancer: Skin Cancer

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Total 74 results found since Jan 2013.

UVB-Induced Secretion of IL-1 < em > β < /em > Promotes Melanogenesis by Upregulating TYR/TRP-1 Expression In Vitro
CONCLUSIONS: UVB-induced melanogenesis is mediated in part by IL-1β, leading to upregulation of the TYR/TRP1 expression in melanoma B16 cells. IL-1β can also stimulate the expression of COX-2 and SCF in HaCaT cells, which in turn increase melanin synthesis in melanocytes. These results suggest that anti-inflammatory approaches could possibly mitigate UVB-induced hyperpigmentation.PMID:35572734 | PMC:PMC9106468 | DOI:10.1155/2022/8230646
Source: Biomed Res - May 16, 2022 Category: Research Authors: Chun-Yan Yang Yanni Guo Wen-Juan Wu Mao-Qiang Man Ying Tu Li He Source Type: research

Upregulation of OATP1A2 in human oesophageal squamous cell carcinoma cells via the HDAC6-GCN5/PCAF-H3K9Ac axis
In conclusion, this study indicated that suppression of OATP1A2 would inhibit the progression and prognosis in ESCC.PMID:34823432 | DOI:10.1080/00498254.2021.2001076
Source: Xenobiotica - November 26, 2021 Category: Research Authors: Xiaoli Zheng Jian V Zhang Yanfeng Bai Jiaqi Wang Mingfeng Jiang Su Zeng Lvhua Wang Source Type: research

LINC01303 promotes the proliferation and migration of laryngeal carcinoma by regulating miR-200c/TIMP2 axis
CONCLUSION: LINC01303 plays a carcinogenic part in LSCC carcinogenesis through regulating miR-200c/TIMP2 axis, which may become a promising target of LSCC therapy.PMID:33841686 | PMC:PMC8014399
Source: American Journal of Translational Research - April 12, 2021 Category: Research Authors: Dong Xiao Xiangyan Cui Ning Fang Shujian Yu Xin Wang Source Type: research