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Specialty: Opthalmology
Condition: Diabetes Mellitus
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Total 1 results found since Jan 2013.
Inhibition of Drp1 ameliorates diabetic retinopathy by regulating mitochondrial homeostasis
Exp Eye Res. 2022 Apr 28:109095. doi: 10.1016/j.exer.2022.109095. Online ahead of print.ABSTRACTDiabetic retinopathy (DR) is a potentially blinding complication resulting from diabetes mellitus (DM). Retinal vascular endothelial cells (RMECs) dysfunction occupies an important position in the pathogenesis of DR, and mitochondrial disorders play a vital role in RMECs dysfunction. However, the detailed mechanisms underlying DR-induced mitochondrial disorders in RMECs remain elusive. In the present study, we used High glucose (HG)-induced RMECs in vitro and streptozotocin (STZ)-induced Sprague-Dawley rats in vivo to explore th...
Source: Experimental Eye Research - May 1, 2022 Category: Opthalmology Authors: Meng-Yuan Zhang Lingpeng Zhu Xun Bao Tian-Hua Xie Jiping Cai Jian Zou Wenjuan Wang Shun Gu Yan Li Hong-Ying Li Yong Yao Ting-Ting Wei Source Type: research
