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Specialty: Cytology
Source: Tissue and Cell
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Total 52 results found since Jan 2013.
Stratifin promotes the growth and proliferation of hepatocellular carcinoma
CONCLUSIONS: Our results suggest that SFN may play an important role in HCC progression and may interact with CDC25B to promote malignant progression of HCC, providing a molecular target for future HCC therapy.PMID:36996719 | DOI:10.1016/j.tice.2023.102080
Source: Tissue and Cell - March 30, 2023 Category: Cytology Authors: Xinyu Zhao Enqin Wang Hongkun Xu Lihong Zhang Source Type: research
Regulation of Hippo/YAP signaling pathway ameliorates cochlear hair cell injury by regulating ferroptosis
In conclusion, YAP1 ameliorated cochlear hair cell injury by upregulating FTL and TFRC to suppress ferroptosis.PMID:36889225 | DOI:10.1016/j.tice.2023.102051
Source: Tissue and Cell - March 8, 2023 Category: Cytology Authors: Xiaorong Niu Peng Han Junsong Liu Zichen Chen Xiaoyan Ma Ting Zhang Baiya Li Xudong Ma Source Type: research
Stabilization of hypoxia-inducible factor-1 α alleviates osteoarthritis via interacting with Per2 and resetting the circadian clock
CONCLUSIONS: This study shows that circadian clock resetting caused by DMOG is at least partially mediated by the HIF1α through interaction with the Per2 promoter and proposes DMOG as supportive therapy for OA.PMID:36162153 | DOI:10.1016/j.tice.2022.101942
Source: Tissue and Cell - September 26, 2022 Category: Cytology Authors: Chenzhong Wang Yueqi Zhang Zhe Wang Wei Yu Minji Tong Zuoqin Yan Source Type: research
Protection of propofol on liver ischemia reperfusion injury by regulating Cyp2b10/ Cyp3a25 pathway
Tissue Cell. 2022 Aug 6;78:101891. doi: 10.1016/j.tice.2022.101891. Online ahead of print.ABSTRACTTo verify whether propofol alleviates liver ischemia-reperfusion injury (IRI) in mice by regulating Cyp2b10/ Cyp3a25 pathway. The liver I/R injury in vivo and in vitro model was constructed. The serum level of AST, ALT, ALP and ALB was detected using ELISA. The mRNA and protein expression of Cyp2b10 and Cyp3a25 were determined by qRT-PCR and western blot, respectively. The liver cell activity was assessed by MTT assay. The binding between Cyp2b10 and Cyp3a25 was evaluated by online website prediction, CoIP, and cell transfecti...
Source: Tissue and Cell - August 19, 2022 Category: Cytology Authors: Jinli Wu Chao Yu Xianggang Zeng Yini Xu Chengyi Sun Source Type: research
A < sub > 1 < /sub > and A < sub > 2b < /sub > adenosine receptors regulate GPX4 against ferroptosis of cardiomyocytes in myocardial infarction rat model and in vitro
CONCLUSION: A1AR and A2bAR could regulate GPX4, thereby affecting ferroptosis of cardiomyocytes in a rat model of MIR.PMID:35653908 | DOI:10.1016/j.tice.2022.101828
Source: Tissue and Cell - June 2, 2022 Category: Cytology Authors: Weili Zhang Weiwei Qiao Luning Zuo Source Type: research
Effect of miR-381-3p/FGF7 axis on the osteogenic differentiation of bone marrow mesenchymal stem cells through MEK/ERK signaling pathway
Tissue Cell. 2022 Apr 1;76:101791. doi: 10.1016/j.tice.2022.101791. Online ahead of print.ABSTRACTAlthough microRNAs (miRNAs) exert an important role in the osteogenesis of mesenchymal stem cells (MSCs), the effect of miR-381-3p on the osteogenic differentiation in MBD‑MSCs is still unclear. The BMMSCs from patients with MBD (MBD‑MSC) or normal participants (Normal‑MSC) were isolated and induced to differentiation with dexamethasone. BMMSCs were transfected with miR-381-3p mimic, miR-381-3p inhibitor, and FGF7 siRNA to regulate the expression of miR-381-3p or FGF7. The direct binding between miR-381-3p and FGF7 was p...
Source: Tissue and Cell - April 15, 2022 Category: Cytology Authors: Ling Qiu Jiao Cai Nan Zhang Lei Ma Fang-Yi Fan Xiao-Ming Li Source Type: research
