Filtered By:
Specialty: Laboratory Medicine
Cancer: Epithelial Cancer
This page shows you your search results in order of date.
Order by Relevance | Date
Total 45 results found since Jan 2013.
Systematic Pan-Cancer Analysis and Experimental Verification Identify FOXA1 as an Immunological and Prognostic Biomarker in Epithelial Ovarian Cancer
CONCLUSIONS: Our results predict and validate the function of FOXA1 in promoting EMT and the progression of disease in EOC. Targeting FOXA1 may improve the sensitivity of EOC treatment.PMID:36393971 | PMC:PMC9646314 | DOI:10.1155/2022/9328972
Source: Disease Markers - November 17, 2022 Category: Laboratory Medicine Authors: Kai Wang Chenan Guan Junhui Yu Xing Chen Xianwen Shang Shuangshuang Mei Xingjun Feng Lingzhi Zheng Source Type: research
Epigenetically-regulated miR-30a/c-5p directly target TWF1 and hamper ccRCC cell aggressiveness
Transl Res. 2022 Jun 10:S1931-5244(22)00141-4. doi: 10.1016/j.trsl.2022.06.009. Online ahead of print.ABSTRACTClear cell renal cell carcinoma (ccRCC) is highly prone to metastasize and displays an extremely low 5-year survival rate. Not only miRNAs (miRs) are key gene expression regulators but can also be epigenetically modified. Abnormal miR expression has been linked with epithelial-mesenchymal transition (EMT)-driven ccRCC progression. MiR-30a/c-5p were found downregulated in ccRCC and associated with aggressiveness. Herein, we sought to unravel miR-30a/c-5p mechanistic role in ccRCC. RNA sequencing and genome-wide meth...
Source: Translational Research : the journal of laboratory and clinical medicine - June 13, 2022 Category: Laboratory Medicine Authors: Gon çalo Outeiro-Pinho Daniela Barros-Silva Filipa Moreira-Silva Jo ão Lobo Isa Carneiro Ant ónio Morais Eduarda P Martins C éline S Gonçalves Bruno M Costa Margareta P Correia Rui Henrique Carmen Jer ónimo Source Type: research
Down-Regulation of HBXIP Inhibits Non-Small Cell Lung Cancer Growth and Enhances the Anti-Tumor Immunity of Mice by Reducing NRP-1
CONCLUSION: Down-regulation of HBXIP reduced Lin28B-mediated NRP-1 to suppress NSCLC cell growth and enhance anti-tumor immunity.PMID:34452886
Source: Annals of Clinical and Laboratory Science - August 28, 2021 Category: Laboratory Medicine Authors: Lulu Wang Mao Sun Xing Lin Yongyang Lei Zhe Yin Wei Zhou Source Type: research
