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Nutrition: Organic

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Total 4 results found since Jan 2013.

Organic Cation Transporter I and Na+/taurocholate Co ?Transporting Polypeptide are Involved in Retrorsine? and Senecionine?Induced Hepatotoxicity in HepaRG cells
ConclusionOur results confirm previous findings of active transport mechanisms of PAs into hepatocytes and highlight the importance of toxicokinetic studies for the risk assessment of PAs.
Source: Molecular Nutrition and Food Research - December 11, 2021 Category: Food Science Authors: Anne ?Margarethe Enge, Florian Kaltner, Christoph Gottschalk, Angelina Kin, Michael Kirstgen, Joachim Geyer, Anja These, Helen Hammer, Oliver Pötz, Albert Braeuning, Stefanie Hessel?Pras Tags: Research Article Source Type: research

Organic Cation Transporter I and Na+/taurocholate Co ā€Transporting Polypeptide are Involved in Retrorsineā€ and Senecionineā€Induced Hepatotoxicity in HepaRG cells
ConclusionOur results confirmed previous findings of active transport mechanisms of PAs into hepatocytes and highlight the importance of toxicokinetic studies for the risk assessment of PAs.This article is protected by copyright. All rights reserved
Source: Molecular Nutrition and Food Research - November 26, 2021 Category: Food Science Authors: Anne ā€Margarethe Enge, Florian Kaltner, Christoph Gottschalk, Angelina Kin, Michael Kirstgen, Joachim Geyer, Anja These, Helen Hammer, Oliver Pƶtz, Albert Braeuning, Stefanie Hesselā€Pras Tags: Research Article Source Type: research

Perfluorooctane sulfonate induces autophagy-dependent lysosomal membrane permeabilization by weakened interaction between tyrosinated alpha-tubulin and spinster 1
This study pointed out that SPNS1-tyrosinated Ī±-tubulin interaction mediated the cross-talk between autophagy and LMP induced by PFOS, shedding new light on the mechanism of PFOS hepatotoxicity.PMID:34500008 | DOI:10.1016/j.fct.2021.112540
Source: Food and Chemical Toxicology - September 9, 2021 Category: Food Science Authors: Zhanchen Dong Tianming Qiu Jingyuan Zhang Shanshan Sha Xiuyan Han Jian Kang Xiaoxia Shi Xiance Sun Liping Jiang Guang Yang Xiaofeng Yao Yufang Ma Source Type: research