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Specialty: Cytology
Nutrition: Omega 3
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Total 1 results found since Jan 2013.
Omega‐3 PUFA ethanolamides DHEA and EPEA induce autophagy through PPARγ activation in MCF‐7 breast cancer cells
Abstract
The omega‐3 long chain polyunsaturated fatty acids, docosahexaenoic acid (DHA), and eicosapentaenoic acid (EPA), elicit anti‐proliferative effects in cancer cell lines and in animal models. Dietary DHA and EPA can be converted to their ethanolamide derivatives, docosahexaenoyl ethanolamine (DHEA), and eicosapentaenoyl ethanolamine (EPEA), respectively; however, few studies are reported on their anti‐cancer activities. Here, we demonstrated that DHEA and EPEA were able to reduce cell viability in MCF‐7 breast cancer cells whereas they did not elicit any effects in MCF‐10A non‐tumorigenic breast epitheli...
Source: Journal of Cellular Physiology - February 25, 2013 Category: Cytology Authors: Daniela Rovito, Cinzia Giordano, Donatella Vizza, Pierluigi Plastina, Ines Barone, Ivan Casaburi, Marilena Lanzino, Francesca De Amicis, Diego Sisci, Loredana Mauro, Saveria Aquila, Stefania Catalano, Daniela Bonofiglio, Sebastiano Andò Tags: Original Research Article Source Type: research
