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Source: Stem Cells
Nutrition: Omega 3
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Total 2 results found since Jan 2013.
Increased Lipogenesis Is Critical for Self ‐Renewal and Growth of Breast Cancer Stem Cells: Impact of Omega‐3 Fatty Acids
Breast cancer stem cells (CSC) have a distinct fatty acid profile due to the aberrant expressions of lipogenic enzymes (eg, FAS, SCD1, and FADS1/2), which are highly involved in sustaining their self-renewal, and proliferative capabilities. Omega-3 PUFA can effectively suppress the self-renewal and growth of breast CSC by downregulation of the lipogenic enzymes, especially SCD1. AbstractAberrant lipid metabolism has recently been recognized as a new hallmark of malignancy, but the characteristics of fatty acid metabolism in breast cancer stem cells (BCSC) and potential interventions targeting this pathway remain to be addr...
Source: Stem Cells - September 6, 2021 Category: Stem Cells Authors: Haiqing Luo,
Chih ‐Yu Chen,
Xiangyong Li,
Xin Zhang,
Chien‐Wen Su,
Yinhua Liu,
Tinglan Cao,
Lei Hao,
Meng Wang,
Jing Xuan Kang Tags: Cancer Stem Cells Source Type: research
