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Total 66 results found since Jan 2013.

Cystine induced ‐mTORC2 activation through promoting Sin1 phosphorylation to suppress cancer cell ferroptosis
Conclusion: These results indicate that cystine-induced activation of the p38-Sin1-mTORC2-AKT pathway suppresses ferroptosis.This article is protected by copyright. All rights reserved
Source: Molecular Nutrition and Food Research - October 3, 2022 Category: Food Science Authors: GuoYan Wang, Lei Chen, SenLin Qin, YiNing Zheng, Chao Xia, JunHu Yao, Ping Wang, Lu Deng Tags: Research Article Source Type: research

Intracellular ferritin heavy chain plays the key role in artesunate-induced ferroptosis in ovarian serous carcinoma cells
In conclusion, enhancement of ferritinophagy is an important step involved in the mechanism of Artesunate-induced ferroptosis, and ferritin heavy chain levels may contribute to the regulation of sensitivity in Artesunate-induced ferroptosis in ovarian serous carcinoma cells.PMID:35903602 | PMC:PMC9309081 | DOI:10.3164/jcbn.21-82
Source: Journal of Clinical Biochemistry and Nutrition - July 29, 2022 Category: Nutrition Authors: Tiger Koike Motoki Takenaka Noriko Suzuki Yoko Ueda Minako Mori Tasuku Hirayama Hideko Nagasawa Ken-Ichirou Morishige Source Type: research