Filtered By:
Source: Journal of Cellular Physiology
Nutrition: Glucosamine
This page shows you your search results in order of date.
Order by Relevance | Date
Total 1 results found since Jan 2013.
Glucosamine‐Induced Sp1 O‐GlcNAcylation Ameliorates Hypoxia‐Induced SGLT Dysfunction in Primary Cultured Renal Proximal Tubule Cells
The aim of this study is to determine whether GlcN could recover the endoplasmic reticulum (ER) stress‐induced dysfunction of Na+/glucose cotransporter (SGLT) in renal proximal tubule cells (PTCs) under hypoxia. With the rabbit model, the renal ischemia induced tubulointerstitial abnormalities and decreased SGLTs expression in tubular brush‐border, which were recovered by GlcN. Thus, the protective mechanism of GlcN against renal ischemia was being examined by using PTCs. Hypoxia decreased the level of protein O‐GlcNAc and the expression of O‐GlcNAc transferase (OGT) while increased O‐GlcNAcase (OGA) and these we...
Source: Journal of Cellular Physiology - March 4, 2014 Category: Cytology Authors: Han Na Suh, Yu Jin Lee, Mi Ok Kim, Ho Jae Han Tags: Original Research Article Source Type: research
