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Specialty: Microbiology
Infectious Disease: Yellow Fever

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Total 2 results found since Jan 2013.

Argonaute-CLIP delineates versatile, functional RNAi networks in Aedes aegypti, a major vector of human viruses
Cell Host Microbe. 2021 Mar 29:S1931-3128(21)00132-3. doi: 10.1016/j.chom.2021.03.004. Online ahead of print.ABSTRACTArgonaute (AGO) proteins bind small RNAs to silence complementary RNA transcripts, and they are central to RNA interference (RNAi). RNAi is critical for regulation of gene expression and antiviral defense in Aedes aegypti mosquitoes, which transmit Zika, chikungunya, dengue, and yellow fever viruses. In mosquitoes, AGO1 mediates miRNA interactions, while AGO2 mediates siRNA interactions. We applied AGO-crosslinking immunoprecipitation (AGO-CLIP) for both AGO1 and AGO2, and we developed a universal software p...
Source: Cell Host and Microbe - April 1, 2021 Category: Microbiology Authors: Kathryn Rozen-Gagnon Meigang Gu Joseph M Luna Ji-Dung Luo Soon Yi Sasha Novack Eliana Jacobson Wei Wang Matthew R Paul Troels K H Scheel Thomas Carroll Charles M Rice Source Type: research