• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

MicroRNA-363 targets myosin 1B to reduce cellular migration in head and neck cancer
Conclusions: These findings demonstrate that the overexpression of miR-363 reduces cellular migration in head and neck cancer and reveal the biological relationship between miR-363, myosin 1b, and HPV-positive SCCHN.
Source: BMC Cancer - November 6, 2015 Category: Cancer & Oncology Authors: Bhavana ChapmanAbigail WaldParvez AkhtarAna MunkoJingjing XuSandra GibsonJennifer GrandisRobert FerrisSaleem Khan Source Type: research

Deregulation of microRNAs Let-7a and miR-21 mediate aberrant STAT3 signaling during human papillomavirus-induced cervical carcinogenesis: role of E6 oncoprotein
Conclusions: Our results demonstrate existence of a functional loop involving Let-7a, STAT3 and miR-21 which were found potentially regulated by viral oncoprotein E6. Implications: miR-21 and Let-7a along with STAT3 may prove useful targets for pharmacological intervention for management of cervical cancer.
Source: BMC Cancer - December 23, 2014 Category: Cancer & Oncology Authors: Gauri ShishodiaGaurav VermaYogesh SrivastavaRavi MehrotraBhudev DasAlok Bharti Source Type: research