Filtered By:
Source: Hypertension
Nutrition: Low Fat
This page shows you your search results in order of date.
Order by Relevance | Date
Total 1 results found since Jan 2013.
Adipocyte (Pro)Renin-Receptor Deficiency Induces Lipodystrophy, Liver Steatosis and Increases Blood Pressure in Male Mice Prorenin Receptor
We report a unique model of adipocyte-PRR–deficient mice (PRRAdi/Y) with almost no detectable white adipose tissues. As a consequence, the livers of PRRAdi/Y mice were enlarged and demonstrated a marked accumulation of lipids. Adipocyte-specific deficiency of PRR increased systolic blood pressure and the concentration of soluble PRR in plasma. To determine whether adipocyte-PRR was involved in the development of obesity-induced hypertension, mice were fed a low-fat or a high-fat diet for 16 weeks. Adipocyte-PRR–deficient mice were resistant to diet-induced obesity. Both high-fat– and low-fat–fed PRR...
Source: Hypertension - June 7, 2016 Category: Cardiology Authors: Wu, C.-H., Mohammadmoradi, S., Thompson, J., Su, W., Gong, M., Nguyen, G., Yiannikouris, F. Tags: ACE/Angiotensin Receptors/Renin Angiotensin System, High Blood Pressure, Hypertension Prorenin Receptor Source Type: research
