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Source: Journal of Cellular and Molecular Medicine
Therapy: Gene Therapy
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Otx2 enhances transdifferentiation of M üller cells‐derived retinal stem cells into photoreceptor‐like cells
In conclusion, Otx2 enhances transdifferentiation of MC‐RSCs into photoreceptor‐like cells and this is associated with the inhibition of Wnt signalling. Otx2 is a potential target f or gene therapy of retinal degenerative diseases.
Source: Journal of Cellular and Molecular Medicine - November 19, 2018 Category: Molecular Biology Authors: Yu Xiong,
Hongpei Ji,
Zhipeng You,
Fei Yao,
Rongrong Zhou,
Weitao Song,
Xiaobo Xia Tags: ORIGINAL ARTICLE Source Type: research