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Source: Molecular and Cellular Biochemistry
Condition: Hypertension
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Total 2 results found since Jan 2013.
Activation of AMPK inhibits Galectin-3-induced pulmonary artery smooth muscle cells proliferation by upregulating hippo signaling effector YAP
Mol Cell Biochem. 2021 Apr 2. doi: 10.1007/s11010-021-04131-3. Online ahead of print.ABSTRACTGalectin-3(Gal-3) is an effective regulator in the pathological process of pulmonary arterial hypertension (PAH). However, the detailed mechanisms underlying Gal-3 contribution to PAH are not yet entirely clear. The aim of the present study was to explore these issues. Proliferation of rat pulmonary arterial smooth muscle cells (PASMCs) was determined using 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide (MTT) assay. Small interfering RNA (siRNA) was applied to silence the expression of yes-associated protein (YAP) a...
Source: Molecular and Cellular Biochemistry - April 2, 2021 Category: Biochemistry Authors: Qianqian Zhang Wenge Li Yanting Zhu Qingting Wang Cui Zhai Wenhua Shi Wei Feng Jian Wang Xin Yan Limin Chai Yuqian Chen Cong Li Pengtao Liu Manxiang Li Source Type: research
