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Source: Journal of Cellular Physiology
Cancer: Colon Cancer

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Total 4 results found since Jan 2013.

Overexpression of HOXA4 and HOXA9 genes promotes self ‐renewal and contributes to colon cancer stem cell overpopulation
This article is protected by copyright. All rights reserved
Source: Journal of Cellular Physiology - May 2, 2017 Category: Cytology Authors: Seema Bhatlekar, Vignesh Viswanathan, Jeremy Z. Fields, Bruce M. Boman Tags: RAPID COMMUNICATION Source Type: research

Chemokine (C‐C motif) ligand 5 is involved in tumor‐associated dendritic cell‐mediated colon cancer progression through non‐coding RNA MALAT‐1
In conclusion, the inhibition of CCL5 or CCL5‐related signaling may be an attractive therapeutic target in colon cancer patients. This article is protected by copyright. All rights reserved
Source: Journal of Cellular Physiology - December 24, 2014 Category: Cytology Authors: Jung‐Yu Kan, Deng‐Chyang Wu, Fang‐Jung Yu, Cheng‐Ying Wu, Ya‐Wen Ho, Yen‐Jung Chiu, Shu‐Fang Jian, Jen‐Yu Hung, Jaw‐Yuan Wang, Po‐Lin Kuo Tags: Original Research Article Source Type: research

UCP2‐related mitochondrial pathway participates in oroxylin A‐induced apoptosis in human colon cancer cells
In conclusion, we have demonstrate that UCP2 play a key role in mitochondrial apoptotic pathway; UCP2's inhibition by oroxylin A triggers the MPTP opening, and promotes the apoptosis in CaCo‐2 cells. J. Cell. Physiol. © 2014 Wiley Periodicals, Inc.
Source: Journal of Cellular Physiology - September 24, 2014 Category: Cytology Authors: Chen Qiao, Libin Wei, Qinsheng Dai, Yuxin Zhou, Qian Yin, Zhiyu Li, Yuanming Xiao, Qinglong Guo, Na Lu Tags: Original Research Article Source Type: research

MicroRNA‐195 chemosensitizes colon cancer cells to the chemotherapeutic drug doxorubicin by targeting the first binding site of BCL2L2 mRNA
In this study, we utilized microRNA array and real‐time PCR to verify that some microRNAs including miR‐127, miR‐195, miR‐22, miR‐137 were significantly down‐regulated, while miR‐21, miR‐592 were up‐regulated in both HT29/DOX and LOVO/DOX cell lines. In vitro cell viability assay showed that knockdown of miR‐195 in HT29 and LOVO cells caused a marked inhibition of Dox‐induced cytotoxicity. Moreover, we explored that miR‐195 is involved in repression of BCL2L2 expression through targeting its 3'‐untranslated region, especially the first binding site within its mRNA. Furthermore, down‐regulation o...
Source: Journal of Cellular Physiology - March 22, 2013 Category: Cytology Authors: Juan Qu, Liang Zhao, Pengzhi Zhang, Juan Wang, Ning Xu, Wenjuan Mi, Xingwang Jiang, Changming Zhang, Juan Qu Tags: Original Research Article Source Type: research