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Long Non-Coding RNA LINC01260 Inhibits the Proliferation, Migration and Invasion of Spinal Cord Glioma Cells by Targeting CARD11 Via the NF- κB Signaling Pathway
Conclusions: Our findings demonstrate that overexpression of LINC01260 inhibits spinal cord glioma cell proliferation, migration and invasion by targeting CARD11 via NF- κB signaling suppression.Cell Physiol Biochem 2018;48:1563 –1578
Source: Cellular Physiology and Biochemistry - August 2, 2018 Category: Cytology Source Type: research

Effects of Fibronectin 1 on Cell Proliferation, Senescence and Apoptosis of Human Glioma Cells Through the PI3K/AKT Signaling Pathway
Conclusion: The findings of this study provide evidence highlighting the prominent role played by FN1 in stimulating glioma growth, invasion, and survival through the activation of the PI3K/AKT signaling pathway.Cell Physiol Biochem 2018;48:1382 –1396
Source: Cellular Physiology and Biochemistry - July 26, 2018 Category: Cytology Source Type: research

MicroRNA-29a-3p Downregulation Causes Gab1 Upregulation to Promote Glioma Cell Proliferation
Conclusions: miR-29a-3p downregulation leads to Gab1 upregulation to promote glioma cell proliferation.Cell Physiol Biochem 2018;48:450 –460
Source: Cellular Physiology and Biochemistry - July 17, 2018 Category: Cytology Source Type: research

Anti-Cancer Effect of Cap-Translation Inhibitor 4EGI-1 in Human Glioma U87 Cells: Involvement of Mitochondrial Dysfunction and ER Stress
Conclusion: These data indicate that the use of inhibitors that directly target the translation initiation complex eIF4F could represent a potential novel approach for human glioma therapy.Cell Physiol Biochem 2016;40:1013-1028
Source: Cellular Physiology and Biochemistry - December 9, 2016 Category: Cytology Source Type: research

Evidence for the Inhibition by Temozolomide, an Imidazotetrazine Family Alkylator, of Intermediate-Conductance Ca2+-Activated K+ Channels in Glioma Cells
Conclusion: In addition to the DNA damage it does, its inhibitory effect on IKCa channels accompanied by membrane depolarization could be an important mechanism underlying TMZ-induced antineoplastic actions.Cell Physiol Biochem 2016;38:1727-1742
Source: Cellular Physiology and Biochemistry - May 9, 2016 Category: Cytology Source Type: research

Anti-Cancer Effect of Metabotropic Glutamate Receptor 1 Inhibition in Human Glioma U87 Cells: Involvement of PI3K/Akt/mTOR Pathway
Conclusion: The remarkable efficiency of mGluR1 inhibition to induce cell death in U87 cells may find therapeutic application for the treatment of glioma patients.Cell Physiol Biochem 2015;35:419-432
Source: Cellular Physiology and Biochemistry - January 6, 2015 Category: Cytology Source Type: research