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Apelin‐13 administration protects against ischaemia/reperfusion‐mediated apoptosis through the FoxO1 pathway in high‐fat diet‐induced obesity
Conclusions and ImplicationsThese data reveal apelin as a novel regulator of FoxO1 in cardiac cells and provide evidence for the potential of apelin‐13 in prevention of apoptosis and mitochondrial damage in conditions combining I/R injury and obesity.
Source: British Journal of Pharmacology - April 19, 2016 Category: Drugs & Pharmacology Authors: Frederic Boal, Andrei Timotin, Jessica Roumegoux, Chiara Alfarano, Denis Calise, Rodica Anesia, Angelo Parini, Philippe Valet, Helene Tronchere, Oksana Kunduzova Tags: RESEARCH PAPER Source Type: research

Apelin‐13 administration protects against ischemia/reperfusion‐mediated apoptosis through FoxO1 pathway in high‐fat diet‐induced obesity.
Conclusions and ImplicationsThese data uncover apelin as a novel regulator of FoxO1 in cardiac cells and provide the evidence for the potential of apelin‐13 in prevention of apoptosis and mitochondrial damage in conditions combining I/R injury and obesity.
Source: British Journal of Pharmacology - March 23, 2016 Category: Drugs & Pharmacology Authors: Frederic Boal, Andrei Timotin, Jessica Roumegoux, Chiara Alfarano, Denis Calise, Rodica Anesia, Angelo Parini, Philippe Valet, Helene Tronchere, Oksana Kunduzova Tags: Research Paper Source Type: research