Filtered By:
Specialty: Research
Education: Learning
This page shows you your search results in order of date.
Order by Relevance | Date
Total 2 results found since Jan 2013.
Post-Treatment Sevoflurane Protects Against Hypoxic-Ischemic Brain Injury in Neonatal Rats by Downregulating Histone Methyltransferase G9a and Upregulating Nuclear Factor Erythroid 2-Related Factor 2 (NRF2)
CONCLUSIONS Sevoflurane post-treatment promotes NRF2 expression by inhibiting G9a and H3K9me2, thus alleviating HIBI in neonatal rats.PMID:34059615 | DOI:10.12659/MSM.930042
Source: Medical Science Monitor - June 1, 2021 Category: Research Authors: HuaiMing Wang YiQuan Xu Shuying Zhu XueMing Li HongWei Zhang Source Type: research
Trichostatin A epigenetically increases calpastatin expression, and inhibits calpain activity and calcium‐induced SH‐SY5Y neuronal cell toxicity
This study demonstrates that TSA attenuates calcium‐induced neuronal cell death by the inhibition of calpain activity which is mediated in part by increased calpastatin expression via histone hyperacetylation within calpastatin promoter region. Our study provides a novel mechanism for the neuroprotective effect of HDAC inhibitors on AD.
This article is protected by copyright. All rights reserved.
Source: FEBS Journal - October 18, 2013 Category: Research Authors: Jungwon Seo, Sangmee Ahn Jo, Soojin Hwang, Catherine Jeonghae Byun, Hyeon‐Ju Lee, Du‐Hyong Cho, Dueon Kim, Young Ho Koh, Inho Jo Tags: Original Article Source Type: research
