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Drug: Docetaxel

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Total 178 results found since Jan 2013.

MicroRNA-224 modulates chemosensitivity of breast cancer cells to docetaxel by apoptosis inhibitor 5
CONCLUSION: An inverse association between miR-224 and API-5 in breast cancer cells was revealed. Dysregulation of miR-224 plays a vital role in the acquired DOC resistance of breast cancer and at least partially via targeting API-5.PMID:34076992
Source: Journal of B.U.ON. - June 2, 2021 Category: Cancer & Oncology Authors: Junying Zhang Ya Lu Ye Zhang Yan Chen Wenbo Zhu Hangju Zhu Jianzhong Wu Jinhai Tang Source Type: research

Developmentally regulated GTP-binding protein 2 levels in prostate cancer cell lines impact docetaxel-induced apoptosis
CONCLUSIONS: In prostate cancer cells, DRG2 regulates G2/M arrest after docetaxel treatment. In prostate cancer cells with DRG2 knockdown, apoptosis increases without G2/M arrest in response to docetaxel treatment. These results show that inhibition of DRG2 expression can be useful to enhance docetaxel-induced apoptosis despite low-dose administration in castration-resistant prostate cancer.PMID:34190439 | DOI:10.4111/icu.20200574
Source: Clinical Prostate Cancer - June 30, 2021 Category: Cancer & Oncology Authors: Seong Cheol Kim Won Hyeok Lee Song Hee Kim Abdumadjidov Alisher Abdulkhayevich Jeong Woo Park Young Min Kim Kyung Hyun Moon Sang Hun Lee Sungchan Park Source Type: research

MicroRNA-224 modulates chemosensitivity of breast cancer cells to docetaxel by apoptosis inhibitor 5
CONCLUSION: An inverse association between miR-224 and API-5 in breast cancer cells was revealed. Dysregulation of miR-224 plays a vital role in the acquired DOC resistance of breast cancer and at least partially via targeting API-5.PMID:34076992
Source: Journal of B.U.ON. - June 2, 2021 Category: Cancer & Oncology Authors: Junying Zhang Ya Lu Ye Zhang Yan Chen Wenbo Zhu Hangju Zhu Jianzhong Wu Jinhai Tang Source Type: research

Developmentally regulated GTP-binding protein 2 levels in prostate cancer cell lines impact docetaxel-induced apoptosis
CONCLUSIONS: In prostate cancer cells, DRG2 regulates G2/M arrest after docetaxel treatment. In prostate cancer cells with DRG2 knockdown, apoptosis increases without G2/M arrest in response to docetaxel treatment. These results show that inhibition of DRG2 expression can be useful to enhance docetaxel-induced apoptosis despite low-dose administration in castration-resistant prostate cancer.PMID:34190439 | DOI:10.4111/icu.20200574
Source: Clinical Prostate Cancer - June 30, 2021 Category: Cancer & Oncology Authors: Seong Cheol Kim Won Hyeok Lee Song Hee Kim Abdumadjidov Alisher Abdulkhayevich Jeong Woo Park Young Min Kim Kyung Hyun Moon Sang Hun Lee Sungchan Park Source Type: research

MicroRNA-224 modulates chemosensitivity of breast cancer cells to docetaxel by apoptosis inhibitor 5
CONCLUSION: An inverse association between miR-224 and API-5 in breast cancer cells was revealed. Dysregulation of miR-224 plays a vital role in the acquired DOC resistance of breast cancer and at least partially via targeting API-5.PMID:34076992
Source: Journal of B.U.ON. - June 2, 2021 Category: Cancer & Oncology Authors: Junying Zhang Ya Lu Ye Zhang Yan Chen Wenbo Zhu Hangju Zhu Jianzhong Wu Jinhai Tang Source Type: research