• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Human superoxide dismutase 1 attenuates quinoneimine metabolite formation from mefenamic acid.
In conclusion, we found that SOD1 can serve as a detoxification enzyme for quinoneimines to protect from drug-induced toxicity. PMID: 33259822 [PubMed - as supplied by publisher]
Source: Toxicology - November 28, 2020 Category: Toxicology Authors: Ogiso T, Fukami T, Zhongzhe C, Konishi K, Nakano M, Nakajima M Tags: Toxicology Source Type: research

Activation of GR but not PXR by Dexamethasone Attenuated Acetaminophen Hepatotoxicities via Fgf21 Induction.
In conclusion, via GR activation, DEX induced Fgf21 expression in mouse liver and human hepatoma cells. PMID: 28088388 [PubMed - as supplied by publisher]
Source: Toxicology - January 10, 2017 Category: Toxicology Authors: Vispute SG, Bu P, Le Y, Cheng X Tags: Toxicology Source Type: research